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1.
IL12 integrated into the CAR exodomain converts CD8+ T cells to poly-functional NK-like cells with superior killing of antigen-loss tumors.
Mol Ther
; 30(2): 593-605, 2022 02 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34678512
2.
Designed Ankyrin Repeat Protein (DARPin) to target chimeric antigen receptor (CAR)-redirected T cells towards CD4+ T cells to reduce the latent HIV+ cell reservoir.
Med Microbiol Immunol
; 209(6): 681-691, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32918599
3.
Blocking CD30 on T Cells by a Dual Specific CAR for CD30 and Colon Cancer Antigens Improves the CAR T Cell Response against CD30- Tumors.
Mol Ther
; 27(10): 1825-1835, 2019 10 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31331813
4.
CD28-ζ CAR T Cells Resist TGF-ß Repression through IL-2 Signaling, Which Can Be Mimicked by an Engineered IL-7 Autocrine Loop.
Mol Ther
; 26(9): 2218-2230, 2018 09 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30055872
5.
Functionality and Cell Senescence of CD4/ CD8-Selected CD20 CAR T Cells Manufactured Using the Automated CliniMACS Prodigy® Platform.
Transfus Med Hemother
; 46(1): 47-54, 2019 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31244581
6.
Chimeric antigen receptor T cells targeting Fc µ receptor selectively eliminate CLL cells while sparing healthy B cells.
Blood
; 128(13): 1711-22, 2016 09 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-27535994
7.
Of CARs and TRUCKs: chimeric antigen receptor (CAR) T cells engineered with an inducible cytokine to modulate the tumor stroma.
Immunol Rev
; 257(1): 83-90, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24329791
8.
Superior Therapeutic Index in Lymphoma Therapy: CD30(+) CD34(+) Hematopoietic Stem Cells Resist a Chimeric Antigen Receptor T-cell Attack.
Mol Ther
; 24(8): 1423-34, 2016 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-27112062
9.
Stability and activity of MCSP-specific chimeric antigen receptors (CARs) depend on the scFv antigen-binding domain and the protein backbone.
Cancer Immunol Immunother
; 64(12): 1623-35, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26515978
10.
Survivin blockade sensitizes rhabdomyosarcoma cells for lysis by fetal acetylcholine receptor-redirected T cells.
Am J Pathol
; 182(6): 2121-31, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23562272
11.
Arming cytokine-induced killer cells with chimeric antigen receptors: CD28 outperforms combined CD28-OX40 "super-stimulation".
Mol Ther
; 21(12): 2268-77, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23985696
12.
Eradication of melanomas by targeted elimination of a minor subset of tumor cells.
Proc Natl Acad Sci U S A
; 108(6): 2474-9, 2011 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-21282657
13.
T cells that target carcinoembryonic antigen eradicate orthotopic pancreatic carcinomas without inducing autoimmune colitis in mice.
Gastroenterology
; 143(4): 1095-107.e2, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22750462
14.
A CD19-Anti-ErbB2 scFv Engager Protein Enables CD19-Specific CAR T Cells to Eradicate ErbB2+ Solid Cancer.
Cells
; 12(2)2023 01 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36672182
15.
CAR and TCR form individual signaling synapses and do not cross-activate, however, can co-operate in T cell activation.
Front Immunol
; 14: 1110482, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36817444
16.
Improved activation toward primary colorectal cancer cells by antigen-specific targeting autologous cytokine-induced killer cells.
Clin Dev Immunol
; 2012: 238924, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22481963
17.
CD28 costimulation Impairs the efficacy of a redirected t-cell antitumor attack in the presence of regulatory t cells which can be overcome by preventing Lck activation.
Mol Ther
; 19(4): 760-7, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21326215
18.
Rational development of high-affinity T-cell receptor-like antibodies.
Proc Natl Acad Sci U S A
; 106(14): 5784-8, 2009 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-19307587
19.
Costimulation by chimeric antigen receptors revisited the T cell antitumor response benefits from combined CD28-OX40 signalling.
Int J Cancer
; 129(12): 2935-44, 2011 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22030616
20.
Regulatory T cells with reduced repressor capacities are extensively amplified in pulmonary sarcoid lesions and sustain granuloma formation.
Clin Immunol
; 140(1): 71-83, 2011 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-21482483