Detalles de la búsqueda
1.
Potential Rheumatoid Arthritis-Associated Interstitial Lung Disease Treatment and Computational Approach for Future Drug Development.
Int J Mol Sci
; 25(5)2024 Feb 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-38473928
2.
Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90.
Mol Pharmacol
; 88(2): 245-55, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25976766
3.
6-Phenoxy-2-phenylbenzoxazoles, novel inhibitors of receptor for advanced glycation end products (RAGE).
Bioorg Med Chem
; 23(15): 4919-4935, 2015 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26051601
4.
Two ß-strands of RAGE participate in the recognition and transport of amyloid-ß peptide across the blood brain barrier.
Biochem Biophys Res Commun
; 439(2): 252-7, 2013 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-23973487
5.
Single-cell mechanics provides a sensitive and quantitative means for probing amyloid-beta peptide and neuronal cell interactions.
Proc Natl Acad Sci U S A
; 107(31): 13872-7, 2010 Aug 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-20643929
6.
A differential association of Apolipoprotein E isoforms with the amyloid-ß oligomer in solution.
Proteins
; 79(2): 402-16, 2011 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-21069870
7.
Inhibition of Alzheimer's amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo.
J Neurochem
; 108(4): 1097-1108, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19141069
8.
Syntheses of tricyclic pyrones and pyridinones and protection of Abeta-peptide induced MC65 neuronal cell death.
Bioorg Med Chem Lett
; 19(3): 670-4, 2009 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19121940
9.
Congo red and thioflavin-T analogs detect Abeta oligomers.
J Neurochem
; 104(2): 457-68, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17953662
10.
Discovery of an Orally Bioavailable Benzofuran Analogue That Serves as a ß-Amyloid Aggregation Inhibitor for the Potential Treatment of Alzheimer's Disease.
J Med Chem
; 61(1): 396-402, 2018 01 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-29161514
11.
Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Abeta oligomer-induced cytotoxicity.
Brain Res
; 1130(1): 223-34, 2007 Jan 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-17157826
12.
Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer's Agents Based on Rational Design.
J Med Chem
; 60(6): 2573-2590, 2017 03 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-28234463
13.
Acute ER stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation.
Sci Rep
; 5: 8805, 2015 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-25740315
14.
Tomoregulin (TMEFF2) Binds Alzheimer's Disease Amyloid-ß (Aß) Oligomer and AßPP and Protects Neurons from Aß-Induced Toxicity.
J Alzheimers Dis
; 48(3): 731-43, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26402097
15.
3D Light-Sheet Fluorescence Microscopy of Cranial Neurons and Vasculature during Zebrafish Embryogenesis.
Mol Cells
; 38(11): 975-81, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26429501
16.
Mitochondria-specific accumulation of amyloid ß induces mitochondrial dysfunction leading to apoptotic cell death.
PLoS One
; 7(4): e34929, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22514691
17.
Intracellular amyloid-ß accumulation in calcium-binding protein-deficient neurons leads to amyloid-ß plaque formation in animal model of Alzheimer's disease.
J Alzheimers Dis
; 29(3): 615-28, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22269161
18.
Ligand-based design, synthesis, and biological evaluation of 2-aminopyrimidines, a novel series of receptor for advanced glycation end products (RAGE) inhibitors.
J Med Chem
; 55(21): 9120-35, 2012 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-22742537
19.
The influence of spin-labeled fluorene compounds on the assembly and toxicity of the aß peptide.
PLoS One
; 7(4): e35443, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22558151
20.
Ghrelin ameliorates cognitive dysfunction and neurodegeneration in intrahippocampal amyloid-ß1-42 oligomer-injected mice.
J Alzheimers Dis
; 23(1): 147-59, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-20930280