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1.
Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core structure transformation from the stilbene moiety.
Bioorg Med Chem
; 27(15): 3440-3450, 2019 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31235264
2.
Discovery of 2-[(E)-2-(7-Fluoro-3-methylquinoxalin-2-yl)vinyl]-6-pyrrolidin-1-yl-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine Hydrochloride as a Highly Selective PDE10A Inhibitor.
Chem Pharm Bull (Tokyo)
; 66(3): 243-250, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29491258
3.
C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors.
Bioorg Med Chem
; 21(17): 5561-72, 2013 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23809172
4.
Discovery of canagliflozin, a novel C-glucoside with thiophene ring, as sodium-dependent glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes mellitus.
J Med Chem
; 53(17): 6355-60, 2010 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-20690635
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