Detalles de la búsqueda
1.
Novel insights into presenilin 1 mutation associated with a distinctive dementia phenotype and cotton wool plaques.
Neurol Sci
; 2024 May 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38755484
2.
Nectin-2 is a potential target for antibody therapy of breast and ovarian cancers.
Mol Cancer
; 12: 60, 2013 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-23758976
3.
Anti-angiogenic and anti-tumor effects of TAK-593, a potent and selective inhibitor of vascular endothelial growth factor and platelet-derived growth factor receptor tyrosine kinase.
Cancer Sci
; 104(4): 486-94, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23305239
4.
Structure-based discovery of cellular-active allosteric inhibitors of FAK.
Bioorg Med Chem Lett
; 23(6): 1779-85, 2013 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23414845
5.
Design, synthesis, and evaluation of novel VEGFR2 kinase inhibitors: discovery of [1,2,4]triazolo[1,5-a]pyridine derivatives with slow dissociation kinetics.
Bioorg Med Chem
; 21(15): 4714-29, 2013 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23755884
6.
Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors.
Bioorg Med Chem
; 21(24): 7686-98, 2013 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24216091
7.
Discovery of N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (TAK-593), a highly potent VEGFR2 kinase inhibitor.
Bioorg Med Chem
; 21(8): 2333-2345, 2013 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23498918
8.
A novel pyrrolo[3, 2-d]pyrimidine derivative, as a vascular endothelial growth factor receptor and platelet-derived growth factor receptor tyrosine kinase inhibitor, shows potent antitumor activity by suppression of tumor angiogenesis.
Cancer Sci
; 103(5): 939-44, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22320850
9.
Diffraction-enhanced X-ray imaging under low-temperature conditions: non-destructive observations of clathrate gas hydrates.
J Synchrotron Radiat
; 19(Pt 6): 1038-42, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23093767
10.
Design, synthesis, and evaluation of imidazo[1,2-b]pyridazine derivatives having a benzamide unit as novel VEGFR2 kinase inhibitors.
Bioorg Med Chem
; 20(24): 7051-8, 2012 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23123015
11.
Transition metal abnormalities in progressive dementias.
Biometals
; 25(2): 337-50, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22080191
12.
A Histochemical Analysis of Neurofibrillary Tangles in Olfactory Epithelium, a Study Based on an Autopsy Case of Juvenile Alzheimer's Disease.
Acta Histochem Cytochem
; 55(3): 93-98, 2022 Jun 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-35821750
13.
Biochemical characterization of TAK-593, a novel VEGFR/PDGFR inhibitor with a two-step slow binding mechanism.
Biochemistry
; 50(5): 738-51, 2011 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-21182308
14.
Biochemical characterization of a novel type-II VEGFR2 kinase inhibitor: comparison of binding to non-phosphorylated and phosphorylated VEGFR2.
Bioorg Med Chem
; 19(18): 5342-51, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21885287
15.
Abnormal phospholipids distribution in the prefrontal cortex from a patient with schizophrenia revealed by matrix-assisted laser desorption/ionization imaging mass spectrometry.
Anal Bioanal Chem
; 400(7): 1933-43, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21461619
16.
13C chemical shifts of propane molecules encaged in structure II clathrate hydrate.
J Phys Chem A
; 115(5): 643-7, 2011 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-21229965
17.
Immunohistochemical expression of fibroblast growth factor-2 in developing human cerebrum and epilepsy-associated malformations of cortical development.
Neuropathology
; 31(6): 589-98, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21382096
18.
N-phenyl-N'-[4-(5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as novel inhibitors of VEGFR and FGFR kinases.
Bioorg Med Chem
; 18(20): 7150-63, 2010 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20833551
19.
Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation.
Bioorg Med Chem
; 18(20): 7260-73, 2010 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20833055
20.
Raman peak frequencies of fluoromethane molecules measured in clathrate hydrate crystals: experimental investigations and density functional theory calculations.
J Phys Chem A
; 114(1): 317-23, 2010 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-19916515