Detalles de la búsqueda
1.
Oryza sativa Parkeol Cyclase: Changes in the Substrate-Folding Conformation and the Deprotonation Sites on Mutation at Tyr257: Importance of the Hydroxy Group and Steric Bulk.
Chembiochem
; 20(22): 2862-2875, 2019 11 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-31180162
2.
Enzymatic syntheses of novel carbocyclic scaffolds with a 6,5 + 5,5 ring system by squalene-hopene cyclase.
Org Biomol Chem
; 17(42): 9375-9389, 2019 10 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-31621743
3.
Chemical structure of cichorinotoxin, a cyclic lipodepsipeptide that is produced by Pseudomonas cichorii and causes varnish spots on lettuce.
Beilstein J Org Chem
; 15: 299-309, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30800180
4.
Strictly Conserved Residues in Euphorbia tirucalli ß-Amyrin Cyclase: Trp612 Stabilizes Transient Cation through Cation-π Interaction and CH-π Interaction of Tyr736 with Leu734 Confers Robust Local Protein Architecture.
Chembiochem
; 19(5): 486-495, 2018 03 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29214725
5.
Alicyclobacillus acidocaldarius Squalene-Hopene Cyclase: The Critical Role of Steric Bulk at Ala306 and the First Enzymatic Synthesis of Epoxydammarane from 2,3-Oxidosqualene.
Chembiochem
; 19(17): 1873-1886, 2018 09 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29911308
6.
Squalene-Hopene Cyclase: Mechanistic Insights into the Polycyclization Cascades of Squalene Analogs Bearing Ethyl and Hydroxymethyl Groups at the C-2 and C-23 Positions.
Chemistry
; 24(43): 11139-11157, 2018 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29732636
7.
Mutated variants of squalene-hopene cyclase: enzymatic syntheses of triterpenes bearing oxygen-bridged monocycles and a new 6,6,6,6,6-fusded pentacyclic scaffold, named neogammacerane, from 2,3-oxidosqualene.
Org Biomol Chem
; 16(37): 8365-8378, 2018 09 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-30209480
8.
Euphorbia tirucalli ß-Amyrin Synthase: Critical Roles of Steric Sizes at Val483 and Met729 and the CH-π Interaction between Val483 and Trp534 for Catalytic Action.
Chembiochem
; 18(21): 2145-2155, 2017 11 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28875584
9.
ß-Amyrin biosynthesis: catalytic mechanism and substrate recognition.
Org Biomol Chem
; 15(14): 2869-2891, 2017 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28294269
10.
Correction: ß-Amyrin synthase from Euphorbia tirucalli L. functional analyses of the highly conserved aromatic residues Phe413, Tyr259 and Trp257 disclose the importance of the appropriate steric bulk, and cation-π and CH-π interactions for the efficient catalytic action of the polyolefin cyclization cascade.
Org Biomol Chem
; 15(3): 717, 2017 01 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-28071780
11.
ß-Amyrin Biosynthesis: Promiscuity for Steric Bulk at Position 23 in the Oxidosqualene Substrate and the Significance of Hydrophobic Interaction between the Methyl Group at Position 30 and the Binding Site.
J Org Chem
; 81(15): 6657-71, 2016 08 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27419810
12.
ß-Amyrin synthase from Euphorbia tirucalli L. functional analyses of the highly conserved aromatic residues Phe413, Tyr259 and Trp257 disclose the importance of the appropriate steric bulk, and cation-π and CH-π interactions for the efficient catalytic action of the polyolefin cyclization cascade.
Org Biomol Chem
; 15(1): 177-188, 2016 12 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-27942657
13.
Identification of a new diterpene biosynthetic gene cluster that produces O-methylkolavelool in Herpetosiphon aurantiacus.
Chembiochem
; 16(5): 772-81, 2015 Mar 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-25694050
14.
Non-contrast myocardial perfusion using a novel 4D magnetic resonance arterial spin labeling technique: initial experience.
Microvasc Res
; 98: 94-101, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25645290
15.
ß-Amyrin Biosynthesis: The Methyl-30 Group of (3S)-2,3-Oxidosqualene Is More Critical to Its Correct Folding To Generate the Pentacyclic Scaffold than the Methyl-24 Group.
Chemistry
; 21(44): 15769-84, 2015 Oct 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-26351084
16.
Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis.
J Am Chem Soc
; 136(7): 2892-6, 2014 Feb 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-24475925
17.
ß-Amyrin synthase from Euphorbia tirucalli. Steric bulk, not the π-electrons of Phe, at position 474 has a key role in affording the correct folding of the substrate to complete the normal polycyclization cascade.
Org Biomol Chem
; 12(23): 3836-46, 2014 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-24695673
18.
Cyclization of squalene from both termini: identification of an onoceroid synthase and enzymatic synthesis of ambrein.
J Am Chem Soc
; 135(49): 18335-8, 2013 Dec 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-24274794
19.
Identification of novel sesterterpene/triterpene synthase from Bacillus clausii.
Chembiochem
; 14(7): 822-5, 2013 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-23554321
20.
Effect of cation-π interactions and steric bulk on the catalytic action of oxidosqualene cyclase: a case study of Phe728 of ß-amyrin synthase from Euphorbia tirucalli L.
Chemistry
; 19(50): 17150-8, 2013 Dec 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-24203491