Detalles de la búsqueda
1.
Rational design of small-molecules to recognize G-quadruplexes of c-MYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast cancer.
Nucleic Acids Res
; 50(4): 1829-1848, 2022 02 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-35166828
2.
Chemical intervention of the NM23-H2 transcriptional programme on c-MYC via a novel small molecule.
Nucleic Acids Res
; 43(14): 6677-91, 2015 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-26117539
3.
Stabilization of G-quadruplex DNA by C-5-methyl-cytosine in bcl-2 promoter: implications for epigenetic regulation.
Biochem Biophys Res Commun
; 433(4): 368-73, 2013 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-23261425
4.
2-(2-indolyl-)-4(3H)-quinazolines derivates as new inhibitors of AChE: design, synthesis, biological evaluation and molecular modelling.
J Enzyme Inhib Med Chem
; 28(3): 583-92, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22380775
5.
Development of a universal colorimetric indicator for G-quadruplex structures by the fusion of thiazole orange and isaindigotone skeleton.
Anal Chem
; 84(15): 6288-92, 2012 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-22839657
6.
New insights from molecular dynamic simulation studies of the multiple binding modes of a ligand with G-quadruplex DNA.
J Comput Aided Mol Des
; 26(12): 1355-68, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23239169
7.
Design, synthesis and evaluation of isaindigotone derivatives as dual inhibitors for acetylcholinesterase and amyloid beta aggregation.
Bioorg Med Chem
; 20(8): 2527-34, 2012 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22444876
8.
Studies on the binding of 5-N-methylated quindoline derivative to human telomeric G-quadruplex.
Biochem Biophys Res Commun
; 406(3): 454-8, 2011 Mar 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-21333628
9.
Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.
Org Biomol Chem
; 9(8): 2975-86, 2011 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-21373680
10.
Impact of planarity of unfused aromatic molecules on G-quadruplex binding: learning from isaindigotone derivatives.
Org Biomol Chem
; 9(18): 6422-36, 2011 Sep 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-21808792
11.
A small-sized benzothiazole-indolium fluorescent probe: the study of interaction specificity targeting c-MYC promoter G-quadruplex structures and live cell imaging.
Chem Commun (Camb)
; 56(95): 15016-15019, 2020 Dec 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33185205
12.
Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands.
Bioorg Med Chem Lett
; 19(13): 3414-7, 2009 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19477640
13.
Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.
Bioorg Med Chem Lett
; 18(13): 3790-3, 2008 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18524585
14.
9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc.
Bioorg Med Chem
; 16(16): 7582-91, 2008 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18674916
15.
A study on a telo21 G-quadruplex DNA specific binding ligand: enhancing the molecular recognition ability via the amino group interactions.
RSC Adv
; 8(36): 20222-20227, 2018 May 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-35541662
16.
Correction: A study on a telo21 G-quadruplex DNA specific binding ligand: enhancing the molecular recognition ability via the amino group interactions.
RSC Adv
; 8(41): 22931, 2018 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35543993
17.
Molecular Engineering of Thiazole Orange Dye: Change of Fluorescent Signaling from Universal to Specific upon Binding with Nucleic Acids in Bioassay.
ACS Chem Biol
; 11(4): 1019-29, 2016 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26752011
18.
Investigation on fragmentation pathways of rutaecarpine and its two derivatives using electrospray ionization ion-trap time-of-flight tandem mass spectrometry.
Rapid Commun Mass Spectrom
; 24(18): 2781-6, 2010 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-20814986
19.
Identification of a selective G-quadruplex DNA binder using a multistep virtual screening approach.
Chem Commun (Camb)
; 51(1): 198-201, 2015 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-25388435
20.
3D-QSAR studies of azaoxoisoaporphine, oxoaporphine, and oxoisoaporphine derivatives as anti-AChE and anti-AD agents by the CoMFA method.
J Mol Graph Model
; 41: 61-7, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23500628