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1.
The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (MC3R) Small-Molecule Ligands.
Int J Mol Sci
; 24(12)2023 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37373293
2.
Identification and Pharmacological Characterization of a Low-Liability Antinociceptive Bifunctional MOR/DOR Cyclic Peptide.
Molecules
; 28(22)2023 Nov 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38005269
3.
A Novel Probe for Spliceosomal Proteins that Induces Autophagy and Death of Melanoma Cells Reveals New Targets for Melanoma Drug Discovery.
Cell Physiol Biochem
; 53(4): 656-686, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31573152
4.
Exploring the chemical space of peptides for drug discovery: a focus on linear and cyclic penta-peptides.
Mol Divers
; 22(2): 259-267, 2018 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-29446006
5.
A one-pot multicomponent approach to a new series of morphine derivatives and their biological evaluation.
Org Biomol Chem
; 15(37): 7796-7801, 2017 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-28875208
6.
Small-Molecule Inhibitors Targeting Topoisomerase I as Novel Antituberculosis Agents.
Antimicrob Agents Chemother
; 60(7): 4028-36, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27114277
7.
Identification of 5,6-dihydroimidazo[2,1-b]thiazoles as a new class of antimicrobial agents.
Bioorg Med Chem
; 24(21): 5633-5638, 2016 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27663549
8.
Identification of Small Molecule Inhibitors of Human As(III) S-Adenosylmethionine Methyltransferase (AS3MT).
Chem Res Toxicol
; 28(12): 2419-25, 2015 Dec 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-26577531
9.
Activity of ADAM17 (a disintegrin and metalloprotease 17) is regulated by its noncatalytic domains and secondary structure of its substrates.
J Biol Chem
; 288(31): 22871-9, 2013 Aug 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-23779109
10.
Glycosylation of a disintegrin and metalloprotease 17 affects its activity and inhibition.
Anal Biochem
; 449: 68-75, 2014 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24361716
11.
Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries.
Mol Pharmacol
; 84(3): 314-24, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23788657
12.
Discovery of novel inhibitors of a disintegrin and metalloprotease 17 (ADAM17) using glycosylated and non-glycosylated substrates.
J Biol Chem
; 287(43): 36473-87, 2012 Oct 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-22927435
13.
The role of imidazole in peptide cyclization by transesterification: parallels to the catalytic triads of serine proteases.
Org Biomol Chem
; 11(18): 2979-87, 2013 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-23529282
14.
Conditional probabilistic analysis for prediction of the activity landscape and relative compound activities.
J Chem Inf Model
; 53(10): 2613-25, 2013 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-23971977
15.
Rapid scanning structure-activity relationships in combinatorial data sets: identification of activity switches.
J Chem Inf Model
; 53(6): 1475-85, 2013 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-23705689
16.
Libraries from Libraries: A Series of Sulfonamide Linked Heterocycles Derived from the Same Scaffold.
Tetrahedron Lett
; 54(32)2013 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-24363466
17.
The mathematics of a successful deconvolution: a quantitative assessment of mixture-based combinatorial libraries screened against two formylpeptide receptors.
Molecules
; 18(6): 6408-24, 2013 May 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-23722730
18.
Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity.
Cancer Cell
; 5(1): 25-35, 2004 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-14749124
19.
Identification of B Cell and T Cell Epitopes Using Synthetic Peptide Combinatorial Libraries.
Curr Protoc
; 2(3): e378, 2022 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-35263045
20.
A synthetic combinatorial strategy for developing alpha-conotoxin analogs as potent alpha7 nicotinic acetylcholine receptor antagonists.
J Biol Chem
; 285(3): 1809-21, 2010 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19901032