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1.
Leukemic and non-leukemic lymphocytes from patients with Li Fraumeni syndrome demonstrate loss of p53 function, Bcl-2 family dysregulation and intrinsic resistance to conventional chemotherapeutic drugs but not flavopiridol.
Cell Cycle
; 2(1): 53-8, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-12695689
2.
Increased circulating normal and BCR-ABL+Ve progenitor numbers in Philadelphia chromosome-positive acute myeloid leukaemia.
Leuk Res
; 26(11): 997-1005, 2002 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-12363468
3.
Characterization of psu dic(6;5)(p21.3;q13) with reverse chromosome painting in a patient with secondary myelodysplastic syndrome following treatment for multiple myeloma.
Cancer Genet Cytogenet
; 148(1): 49-54, 2004 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-14697641
4.
Bryostatin induces protein kinase C modulation, Mcl-1 up-regulation and phosphorylation of Bcl-2 resulting in cellular differentiation and resistance to drug-induced apoptosis in B-cell chronic lymphocytic leukemia cells.
Leuk Lymphoma
; 45(5): 997-1008, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15291360
5.
Antisense oligonucleotides complementary to Bax transcripts reduce the susceptibility of B-cell chronic lymphocytic leukaemia cells to apoptosis in a bcl-2 independent manner.
Leuk Lymphoma
; 43(10): 2003-9, 2002 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-12481899
6.
Flavopiridol induces apoptosis in B-cell chronic lymphocytic leukaemia cells through a p38 and ERK MAP kinase-dependent mechanism.
Leuk Lymphoma
; 44(2): 337-42, 2003 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-12688354
7.
The vitamin D3 analog EB1089 induces apoptosis via a p53-independent mechanism involving p38 MAP kinase activation and suppression of ERK activity in B-cell chronic lymphocytic leukemia cells in vitro.
Blood
; 101(7): 2454-60, 2003 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12446453
8.
The P2X7 receptor gene polymorphism 1513 A-->C has no effect on clinical prognostic markers, in vitro sensitivity to fludarabine, Bcl-2 family protein expression or survival in B-cell chronic lymphocytic leukaemia.
Br J Haematol
; 123(1): 66-71, 2003 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-14510944
9.
Protein kinase C mediates mutant N-Ras-induced developmental abnormalities in normal human erythroid cells.
Blood
; 100(12): 4185-92, 2002 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12393454
10.
Retinoid-induced apoptosis in B-cell chronic lymphocytic leukaemia cells is mediated through caspase-3 activation and is independent of p53, the retinoic acid receptor, and differentiation.
Eur J Haematol
; 69(4): 227-35, 2002 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-12431242
11.
The AML1-ETO fusion gene promotes extensive self-renewal of human primary erythroid cells.
Blood
; 101(2): 624-32, 2003 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12393523
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