Detalles de la búsqueda
1.
Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors.
Bioorg Chem
; 98: 103689, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32171993
2.
Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity.
J Biomed Sci
; 25(1): 6, 2018 Jan 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-29361943
3.
Mycotoxin Patulin Suppresses Innate Immune Responses by Mitochondrial Dysfunction and p62/Sequestosome-1-dependent Mitophagy.
J Biol Chem
; 291(37): 19299-311, 2016 09 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27458013
4.
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules.
Proc Natl Acad Sci U S A
; 110(19): E1779-87, 2013 May 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-23610398
5.
Epstein-Barr virus BALF3 has nuclease activity and mediates mature virion production during the lytic cycle.
J Virol
; 88(9): 4962-75, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24554665
6.
Reticulon 3 interacts with NS4B of the hepatitis C virus and negatively regulates viral replication by disrupting NS4B self-interaction.
Cell Microbiol
; 16(11): 1603-18, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24898729
7.
Identification of ligand efficient, fragment-like hits from an HTS library: structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity.
J Comput Aided Mol Des
; 29(1): 89-100, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25344840
8.
Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3).
Bioorg Med Chem
; 21(11): 2856-67, 2013 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23618709
9.
Identification of BPR3P0128 as an inhibitor of cap-snatching activities of influenza virus.
Antimicrob Agents Chemother
; 56(2): 647-57, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-21930871
10.
Development of an anti-influenza drug screening assay targeting nucleoproteins with tryptophan fluorescence quenching.
Anal Chem
; 84(15): 6391-9, 2012 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-22712523
11.
Enhanced recombinant protein production and differential expression of molecular chaperones in sf-caspase-1-repressed stable cells after baculovirus infection.
BMC Biotechnol
; 12: 83, 2012 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-23134743
12.
3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3).
Bioorg Med Chem Lett
; 22(14): 4654-9, 2012 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22726931
13.
Synergistic inhibition of enterovirus 71 replication by interferon and rupintrivir.
J Infect Dis
; 203(12): 1784-90, 2011 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21536800
14.
Extracellular HSP90α Induces MyD88-IRAK Complex-Associated IKKα/ß-NF-κB/IRF3 and JAK2/TYK2-STAT-3 Signaling in Macrophages for Tumor-Promoting M2-Polarization.
Cells
; 11(2)2022 01 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35053345
15.
Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3).
Bioorg Med Chem
; 19(14): 4173-82, 2011 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21708468
16.
Diosgenin, a plant-derived sapogenin, exhibits antiviral activity in vitro against hepatitis C virus.
J Nat Prod
; 74(4): 580-4, 2011 Apr 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-21391660
17.
Inhibition of enterovirus 71 replication and the viral 3D polymerase by aurintricarboxylic acid.
J Antimicrob Chemother
; 65(4): 676-83, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20089540
18.
BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses.
J Antimicrob Chemother
; 65(1): 63-71, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19892833
19.
Development of NS3/4A protease-based reporter assay suitable for efficiently assessing hepatitis C virus infection.
Antimicrob Agents Chemother
; 53(11): 4825-34, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19721068
20.
Anti-HSV activity of digitoxin and its possible mechanisms.
Antiviral Res
; 79(1): 62-70, 2008 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-18353452