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1.
A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin-induced apoptosis in castration-resistant prostate cancer.
Prostate
; 84(6): 605-619, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38375594
2.
Mechanistic study of dual-function inhibitors targeting topoisomerase II and Rad51-mediated DNA repair pathway against castration-resistant prostate cancer.
Prostate
; 83(16): 1549-1563, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37583103
3.
Anticancer Activity and Molecular Mechanisms of an Ursodeoxycholic Acid Methyl Ester-Dihydroartemisinin Hybrid via a Triazole Linkage in Hepatocellular Carcinoma Cells.
Molecules
; 28(5)2023 Mar 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36903603
4.
Discovery of New Glucose Uptake Inhibitors as Potential Anticancer Agents by Non-Radioactive Cell-Based Assays.
Molecules
; 27(22)2022 Nov 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36432207
5.
Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death Against Human Non-Small Cell Lung Cancers.
Int J Mol Sci
; 21(16)2020 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32764382
6.
Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism Studies.
Molecules
; 25(24)2020 Dec 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-33339319
7.
The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis.
Molecules
; 25(12)2020 Jun 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32630532
8.
Effects of lipopolysaccharide on the expression of plasma membrane monoamine transporter (PMAT) at the blood-brain barrier and its implications to the transport of neurotoxins.
J Neurochem
; 135(6): 1178-88, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26376205
9.
Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway.
Prostate
; 75(13): 1454-66, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26180030
10.
Sensitization of cancer cells to paclitaxel-induced apoptosis by canagliflozin.
Biochem Pharmacol
; 223: 116140, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38513740
11.
Doxazosin inhibits vasculogenic mimicry in human nonsmall cell lung cancer through inhibition of the VEGFA/VEcadherin/mTOR/MMP pathway.
Oncol Lett
; 27(4): 170, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38455663
12.
Cardenolide glycosides sensitize gefitinib-induced apoptosis in non-small cell lung cancer: inhibition of Na+/K+-ATPase serving as a switch-on mechanism.
Naunyn Schmiedebergs Arch Pharmacol
; 2024 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38451282
13.
Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulation.
Prostate
; 73(2): 133-45, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22674285
14.
Synthesis and biological evaluation of novel C-aryl d-glucofuranosides as sodium-dependent glucose co-transporter 2 inhibitors.
Bioorg Med Chem
; 21(21): 6282-91, 2013 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24071445
15.
Design, Synthesis, and Evaluation of Glucose Transporter Inhibitor-SN38 Conjugates for Targeting Colorectal Cancer.
J Med Chem
; 66(14): 9684-9696, 2023 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37413981
16.
Development of hemiasterlin derivatives as potential anticancer agents that inhibit tubulin polymerization and synergize with a stilbene tubulin inhibitor.
Invest New Drugs
; 30(4): 1379-88, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21655917
17.
The Combination of a Novel GLUT1 Inhibitor and Cisplatin Synergistically Inhibits Breast Cancer Cell Growth By Enhancing the DNA Damaging Effect and Modulating the Akt/mTOR and MAPK Signaling Pathways.
Front Pharmacol
; 13: 879748, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35662690
18.
Characterization of a fluorescent glucose derivative 1-NBDG and its application in the identification of natural SGLT1/2 inhibitors.
J Food Drug Anal
; 29(3): 521-532, 2021 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35696243
19.
Targeting Colorectal Cancer with Conjugates of a Glucose Transporter Inhibitor and 5-Fluorouracil.
J Med Chem
; 64(8): 4450-4461, 2021 04 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-33819035
20.
Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling.
Front Oncol
; 10: 1274, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32850387