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1.
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules.
Proc Natl Acad Sci U S A
; 110(19): E1779-87, 2013 May 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-23610398
2.
Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design.
Eur J Med Chem
; 229: 114043, 2022 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34929581
3.
Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2).
J Med Chem
; 64(15): 11288-11301, 2021 08 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34337952
4.
Unique Sulfur-Aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors.
J Med Chem
; 63(4): 1642-1659, 2020 02 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31961685
5.
Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants.
J Med Chem
; 62(8): 3940-3957, 2019 04 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-30968693
6.
Identification of a Multitargeted Tyrosine Kinase Inhibitor for the Treatment of Gastrointestinal Stromal Tumors and Acute Myeloid Leukemia.
J Med Chem
; 62(24): 11135-11150, 2019 12 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-31721578
7.
Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1.
J Med Chem
; 59(1): 282-93, 2016 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-26642377
8.
Correction to Unique Sulfur-Aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors.
J Med Chem
; 63(13): 7445, 2020 Jul 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32573230
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