Detalles de la búsqueda
1.
Genetic loss of Nrf1 and Nrf2 leads to distinct metabolism reprogramming of HepG2 cells by opposing regulation of the PI3K-AKT-mTOR signalling pathway.
Bioorg Chem
; 145: 107212, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38377819
2.
Different Inhibition of Nrf2 by Two Keap1 Isoforms α and ß to Shape Malignant Behaviour of Human Hepatocellular Carcinoma.
Int J Mol Sci
; 23(18)2022 Sep 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36142252
3.
Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N-terminal polypeptides during maturation of the CNC-bZIP factor.
Toxicol Appl Pharmacol
; 360: 160-184, 2018 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30268580
4.
Mechanisms controlling the multistage post-translational processing of endogenous Nrf1α/TCF11 proteins to yield distinct isoforms within the coupled positive and negative feedback circuits.
Toxicol Appl Pharmacol
; 360: 212-235, 2018 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30287392
5.
Nach Is a Novel Subgroup at an Early Evolutionary Stage of the CNC-bZIP Subfamily Transcription Factors from the Marine Bacteria to Humans.
Int J Mol Sci
; 19(10)2018 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-30261635
6.
Nrf1D Is the First Candidate Secretory Transcription Factor in the Blood Plasma, Its Precursor Existing as a Unique Redox-Sensitive Transmembrane CNC-bZIP Protein in Hemopoietic and Somatic Tissues.
Int J Mol Sci
; 19(10)2018 Sep 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-30261697
7.
Stability and efficacy of frozen and lyophilized fecal microbiota transplant (FMT) product in a mouse model of Clostridium difficile infection (CDI).
Anaerobe
; 48: 110-114, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28801119
8.
Keap1-Nrf2 pathway: a key mechanism in the occurrence and development of cancer.
Front Oncol
; 14: 1381467, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38634043
9.
Loss of Nrf1 rather than Nrf2 leads to inflammatory accumulation of lipids and reactive oxygen species in human hepatoma cells, which is alleviated by 2-bromopalmitate.
Biochim Biophys Acta Mol Cell Res
; 1871(2): 119644, 2024 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-37996059
10.
Distinct mechanisms by which Nrf1 and Nrf2 as drug targets contribute to the anticancer efficacy of cisplatin on hepatoma cells.
Free Radic Biol Med
; 213: 488-511, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38278308
11.
A novel crosstalk between Nrf2 and Smad2/3 bridged by two nuanced Keap1 isoforms with their divergent effects on these distinct family transcription factors.
Free Radic Biol Med
; 213: 190-207, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38242246
12.
STC2 is a potential biomarker of hepatocellular carcinoma with its expression being upregulated in Nrf1α-deficient cells, but downregulated in Nrf2-deficient cells.
Int J Biol Macromol
; 253(Pt 8): 127575, 2023 Dec 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-37866563
13.
Nrf1 is not a direct target gene of SREBP1, albeit both are integrated into the rapamycin-responsive regulatory network in human hepatoma cells.
PLoS One
; 18(11): e0294508, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38011090
14.
Activation of the membrane-bound Nrf1 transcription factor by USP19, a ubiquitin-specific protease C-terminally anchored in the endoplasmic reticulum.
Biochim Biophys Acta Mol Cell Res
; 1869(9): 119299, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35613680
15.
The Role of MicroRNA in the Regulation of Tumor Epithelial-Mesenchymal Transition.
Cells
; 11(13)2022 06 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35805066
16.
Suppressing the activity of CXCR4 down-regulates the expression of renal fibrosis related genes in primary glomerular cells.
Transl Pediatr
; 11(6): 882-890, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35800283
17.
Distinct Roles of Nrf1 and Nrf2 in Monitoring the Reductive Stress Response to Dithiothreitol (DTT).
Antioxidants (Basel)
; 11(8)2022 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36009254
18.
Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks.
Redox Biol
; 57: 102470, 2022 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-36174386
19.
TCF11 Has a Potent Tumor-Repressing Effect Than Its Prototypic Nrf1α by Definition of Both Similar Yet Different Regulatory Profiles, With a Striking Disparity From Nrf2.
Front Oncol
; 11: 707032, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34268128
20.
Synergism and Antagonism of Two Distinct, but Confused, Nrf1 Factors in Integral Regulation of the Nuclear-to-Mitochondrial Respiratory and Antioxidant Transcription Networks.
Oxid Med Cell Longev
; 2020: 5097109, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33376579