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1.
CPL207280, a Novel G Protein-Coupled Receptor 40/Free Fatty Acid Receptor 1-Specific Agonist, Shows a Favorable Safety Profile and Exerts Antidiabetic Effects in Type 2 Diabetic Animals.
Mol Pharmacol
; 100(4): 335-347, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34349026
2.
A novel JAK/ROCK inhibitor, CPL409116, demonstrates potent efficacy in the mouse model of systemic lupus erythematosus.
J Pharmacol Sci
; 145(4): 340-348, 2021 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-33712286
3.
Preclinical characterization of CPL304110 as a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3 for gastric, bladder, and squamous cell lung cancer.
Front Oncol
; 13: 1293728, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38282676
4.
A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects.
Front Pharmacol
; 13: 999685, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36438799
5.
Design, Synthesis, and Development of pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part I-Indole Derivatives.
Pharmaceuticals (Basel)
; 15(8)2022 Jul 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36015098
6.
Discovery and optimization of novel pyrazole-benzimidazole CPL304110, as a potent and selective inhibitor of fibroblast growth factor receptors FGFR (1-3).
Eur J Med Chem
; 210: 112990, 2021 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33199155
7.
Preclinical characterization of CPL302-253, a selective inhibitor of PI3Kδ, as the candidate for the inhalatory treatment and prevention of Asthma.
PLoS One
; 15(7): e0236159, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32702053
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