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1.
Abundance of Phase 1 and 2 Drug-Metabolizing Enzymes in Alcoholic and Hepatitis C Cirrhotic Livers: A Quantitative Targeted Proteomics Study.
Drug Metab Dispos
; 46(7): 943-952, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29695616
2.
Physiologically-based pharmacokinetic modelling of a CYP2C19 substrate, BMS-823778, utilizing pharmacogenetic data.
Br J Clin Pharmacol
; 84(6): 1335-1345, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29469197
3.
In Vitro Metabolite Formation in Human Hepatocytes and Cardiomyocytes and Metabolism and Tissue Distribution in Monkeys of the 2'-C-Methylguanosine Prodrug BMS-986094 : Potential Role in Clinical Cardiovascular Toxicity.
Int J Toxicol
; 36(1): 35-49, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28056568
4.
Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition.
J Pharmacol Exp Ther
; 358(3): 397-404, 2016 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-27317801
5.
Metabolism and disposition of [14C]BMS-690514, an ErbB/vascular endothelial growth factor receptor inhibitor, after oral administration to humans.
Drug Metab Dispos
; 38(11): 2049-59, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20668249
6.
Algorithm for thorough background subtraction of high-resolution LC/MS data: application to obtain clean product ion spectra from nonselective collision-induced dissociation experiments.
Anal Chem
; 81(7): 2695-700, 2009 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19254033
7.
Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.
J Med Chem
; 51(5): 1145-9, 2008 Mar 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-18260618
8.
Lacteal secretion, fetal and maternal tissue distribution of dasatinib in rats.
Drug Metab Dispos
; 36(12): 2564-70, 2008 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18787054
9.
(D)-2-tert-Butoxycarbonylamino-5,5-difluoro-5-phenyl-pentanoic acid: synthesis and incorporation into the growth hormone secretagogues.
Bioorg Med Chem Lett
; 18(14): 4072-4, 2008 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18554903
10.
Aglycone exploration of C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2.
Bioorg Med Chem Lett
; 18(17): 4770-3, 2008 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18707880
11.
Design and synthesis of tetrazole-based growth hormone secretagogue: the SAR studies of the O-benzyl serine side chain.
Bioorg Med Chem Lett
; 18(6): 1825-9, 2008 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18295486
12.
Discovery of a tetrazole-based growth hormone secretagogue: 4-(hydroxybutyl)carbamic acid 2-{5-[1-(2-amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl ester (BMS-317180).
J Med Chem
; 50(24): 5890-3, 2007 Nov 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-17973363
13.
Discovery of aminothiazole inhibitors of cyclin-dependent kinase 2: synthesis, X-ray crystallographic analysis, and biological activities.
J Med Chem
; 45(18): 3905-27, 2002 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-12190313
14.
A semi-automated method for the integrated evaluation of half-life and metabolic soft spots of discovery compounds.
Bioanalysis
; 4(14): 1747-61, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22877221
15.
Liquid chromatography and tandem mass spectrometry method for the quantitative determination of saxagliptin and its major pharmacologically active 5-monohydroxy metabolite in human plasma: method validation and overcoming specific and non-specific binding at low concentrations.
J Chromatogr B Analyt Technol Biomed Life Sci
; 889-890: 77-86, 2012 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22349123
16.
Information provided to patients undergoing gastroscopy procedures.
J Clin Nurs
; 12(6): 899-911, 2003 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-14632983
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