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1.
Intra-S phase checkpoint kinase Chk1 dissociates replication proteins Treslin and TopBP1 through multiple mechanisms during replication stress.
J Biol Chem
; 298(4): 101777, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35231445
2.
DAGBagM: learning directed acyclic graphs of mixed variables with an application to identify protein biomarkers for treatment response in ovarian cancer.
BMC Bioinformatics
; 23(1): 321, 2022 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35931981
3.
Glycogen Synthase Kinase 3 (GSK-3)-mediated Phosphorylation of Uracil N-Glycosylase 2 (UNG2) Facilitates the Repair of Floxuridine-induced DNA Lesions and Promotes Cell Survival.
J Biol Chem
; 291(52): 26875-26885, 2016 Dec 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-27875297
4.
Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous Recombination.
Mol Pharmacol
; 89(1): 53-62, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26494862
5.
Ovarian cancer-associated mutations disable catalytic activity of CDK12, a kinase that promotes homologous recombination repair and resistance to cisplatin and poly(ADP-ribose) polymerase inhibitors.
J Biol Chem
; 289(13): 9247-53, 2014 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-24554720
6.
Identification of DNA repair pathways that affect the survival of ovarian cancer cells treated with a poly(ADP-ribose) polymerase inhibitor in a novel drug combination.
Mol Pharmacol
; 82(4): 767-76, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22833573
7.
Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer.
Cell Rep Med
; 2(12): 100471, 2021 12 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35028612
8.
ZC3H18 specifically binds and activates the BRCA1 promoter to facilitate homologous recombination in ovarian cancer.
Nat Commun
; 10(1): 4632, 2019 10 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31604914
9.
BRCA1 Deficiency Upregulates NNMT, Which Reprograms Metabolism and Sensitizes Ovarian Cancer Cells to Mitochondrial Metabolic Targeting Agents.
Cancer Res
; 79(23): 5920-5929, 2019 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31619387
10.
Randomized phase II trial of cytosine arabinoside with and without the CHK1 inhibitor MK-8776 in relapsed and refractory acute myeloid leukemia.
Leuk Res
; 61: 108-116, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28957699
11.
Increased thymic output in HIV-negative patients after antiretroviral therapy.
AIDS
; 19(14): 1467-72, 2005 Sep 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-16135899
12.
ATR inhibition broadly sensitizes ovarian cancer cells to chemotherapy independent of BRCA status.
Cancer Res
; 73(12): 3683-91, 2013 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23548269
13.
Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.
PLoS One
; 6(12): e28862, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-22194930
14.
Poly(ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells.
Cancer Res
; 71(14): 4944-54, 2011 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21613406
15.
RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network.
J Cell Biol
; 191(2): 249-57, 2010 Oct 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-20937699
16.
Heat shock protein 90 inhibition depletes LATS1 and LATS2, two regulators of the mammalian hippo tumor suppressor pathway.
Cancer Res
; 70(21): 8642-50, 2010 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20841485
17.
CD28 ligation costimulates cell death but not maturation of double-positive thymocytes due to defective ERK MAPK signaling.
J Immunol
; 177(9): 6098-107, 2006 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17056536
18.
Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice.
J Immunol
; 176(1): 291-300, 2006 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16365421
19.
CAML is a p56Lck-interacting protein that is required for thymocyte development.
Immunity
; 23(2): 139-52, 2005 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16111633
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