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1.
Phosphatidylserine-targeting antibodies augment the anti-tumorigenic activity of anti-PD-1 therapy by enhancing immune activation and downregulating pro-oncogenic factors induced by T-cell checkpoint inhibition in murine triple-negative breast cancers.
Breast Cancer Res
; 18(1): 50, 2016 05 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27169467
2.
Synthesis and evaluation against hepatitis C virus of 7-deaza analogues of 2'-C-methyl-6-O-methyl guanosine nucleoside and L-Alanine ester phosphoramidates.
Bioorg Med Chem Lett
; 23(7): 2260-4, 2013 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23453067
3.
Stable nebulization and muco-trapping properties of regdanvimab/IN-006 support its development as a potent, dose-saving inhaled therapy for COVID-19.
Bioeng Transl Med
; : e10391, 2022 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36248234
4.
Pharmacokinetics and safety of FV-100, a novel oral anti-herpes zoster nucleoside analogue, administered in single and multiple doses to healthy young adult and elderly adult volunteers.
Antimicrob Agents Chemother
; 55(6): 2847-54, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21444712
5.
INX-08189, a phosphoramidate prodrug of 6-O-methyl-2'-C-methyl guanosine, is a potent inhibitor of hepatitis C virus replication with excellent pharmacokinetic and pharmacodynamic properties.
Antimicrob Agents Chemother
; 55(5): 1843-51, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21357300
6.
Dual pro-drugs of 2'-C-methyl guanosine monophosphate as potent and selective inhibitors of hepatitis C virus.
Bioorg Med Chem Lett
; 21(19): 6007-12, 2011 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21856153
7.
Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus.
Bioorg Med Chem Lett
; 20(16): 4850-4, 2010 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20637609
8.
Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats.
J Pharmacol Exp Ther
; 326(1): 41-50, 2008 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-18434589
9.
Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression.
Mol Cancer Res
; 15(6): 753-764, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28184013
10.
Antibody-Mediated Phosphatidylserine Blockade Enhances the Antitumor Responses to CTLA-4 and PD-1 Antibodies in Melanoma.
Cancer Immunol Res
; 4(6): 531-40, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27045021
11.
Phosphorodiamidates as a promising new phosphate prodrug motif for antiviral drug discovery: application to anti-HCV agents.
J Med Chem
; 54(24): 8632-45, 2011 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-22039920
12.
Phosphoramidate ProTides of 2'-C-methylguanosine as highly potent inhibitors of hepatitis C virus. Study of their in vitro and in vivo properties.
J Med Chem
; 53(13): 4949-57, 2010 Jul 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-20527890
13.
Monoclonal antibodies specific for Candida albicans Als3 that immunolabel fungal cells in vitro and in vivo and block adhesion to host surfaces.
J Microbiol Methods
; 78(1): 71-8, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19427882
14.
Automated sample preparation facilitated by PhyNexus MEA purification system for oligosaccharide mapping of glycoproteins.
Anal Biochem
; 369(2): 202-9, 2007 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17716618
15.
A panel of monoclonal antibodies recognizing the Staphylococcus epidermidis fibrinogen-binding MSCRAMM SdrG.
Hybridoma (Larchmt)
; 26(1): 28-34, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17316083
16.
Monoclonal antibodies recognizing the Enterococcus faecalis collagen-binding MSCRAMM Ace: conditional expression and binding analysis.
Microb Pathog
; 43(2-3): 55-66, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17521860
17.
Characterization of a humanized monoclonal antibody recognizing clumping factor A expressed by Staphylococcus aureus.
Infect Immun
; 73(8): 5229-32, 2005 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16041045
18.
Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.
Proc Natl Acad Sci U S A
; 102(44): 16078-83, 2005 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16249345
19.
In vivo expression of a GST-fusion protein mediates the rapid generation of affinity matured monoclonal antibodies using DNA-based immunizations.
Hybrid Hybridomics
; 21(4): 237-43, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12193276
20.
Characterization of a protective monoclonal antibody recognizing Staphylococcus aureus MSCRAMM protein clumping factor A.
Infect Immun
; 71(12): 6864-70, 2003 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-14638774
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