Detalles de la búsqueda
1.
Allosteric modulation of an excitatory amino acid transporter: the subtype-selective inhibitor UCPH-101 exerts sustained inhibition of EAAT1 through an intramonomeric site in the trimerization domain.
J Neurosci
; 33(3): 1068-87, 2013 Jan 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-23325245
2.
Profiling substrate specificity of two series of phenethylamine analogs at monoamine oxidase A and B.
Org Biomol Chem
; 12(43): 8689-95, 2014 Nov 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-25253656
3.
Design, synthesis and pharmacological characterization of coumarin-based fluorescent analogs of excitatory amino acid transporter subtype 1 selective inhibitors, UCPH-101 and UCPH-102.
Bioorg Med Chem
; 20(23): 6831-9, 2012 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23072958
4.
Design and Synthesis of a Series of l-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid.
J Med Chem
; 60(1): 441-457, 2017 01 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-28005385
5.
New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III.
J Med Chem
; 59(3): 914-24, 2016 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-26814576
6.
New Insight into the Structure-Activity Relationships of the Selective Excitatory Amino Acid Transporter Subtypeâ 1 (EAAT1) Inhibitors UCPH-101 and UCPH-102.
ChemMedChem
; 11(4): 382-402, 2016 Feb 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-26757239
7.
Bioavailability Studies and inâ vitro Profiling of the Selective Excitatory Amino Acid Transporter Subtypeâ 1 (EAAT1) Inhibitor UCPH-102.
ChemMedChem
; 11(4): 403-19, 2016 Feb 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-26797816
8.
Structure-activity relationship study of selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitor 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101) and absolute configurational assignment using infrared and vibrational circular dichroism spectroscopy in combination with ab initio Hartree-Fock calculations.
J Med Chem
; 55(11): 5403-12, 2012 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-22594609
9.
Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101).
J Med Chem
; 53(19): 7180-91, 2010 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-20857912
10.
A versatile approach to beta-amyloid fibril-binding compounds exploiting the Shirakawa/Hayashi protocol for trans-alkene synthesis.
Org Lett
; 11(4): 999-1002, 2009 Feb 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-19161320
11.
An expedient synthesis of the fibril binding compound FSB via sequential Pd-catalyzed coupling reactions.
J Org Chem
; 73(9): 3570-3, 2008 May 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-18363363
Resultados
1 -
11
de 11
1
Próxima >
>>