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1.
Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer.
EBioMedicine
; 90: 104500, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-36893587
2.
Design of novel FLT-3 inhibitors based on dual-layer 3D-QSAR model and fragment-based compounds in silico.
J Chem Inf Model
; 52(1): 146-55, 2012 Jan 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-22142286
3.
Pharmacophore modeling and virtual screening to identify potential RET kinase inhibitors.
Bioorg Med Chem Lett
; 21(15): 4490-7, 2011 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21724393
4.
Inhibition of Retinal Ganglion Cell Loss By a Novel ROCK Inhibitor (E212) in Ischemic Optic Nerve Injury Via Antioxidative and Anti-Inflammatory Actions.
Invest Ophthalmol Vis Sci
; 62(6): 21, 2021 05 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34015079
5.
The Intraocular Pressure Lowering Effect of a Dual Kinase Inhibitor (ITRI-E-(S)4046) in Ocular Hypertensive Animal Models.
Invest Ophthalmol Vis Sci
; 62(13): 12, 2021 10 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-34661609
6.
Novel azulene-based derivatives as potent multi-receptor tyrosine kinase inhibitors.
Bioorg Med Chem Lett
; 20(20): 6129-32, 2010 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20833039
7.
Synthesis and structure-activity relationship of 6-arylureido-3-pyrrol-2-ylmethylideneindolin-2-one derivatives as potent receptor tyrosine kinase inhibitors.
Bioorg Med Chem
; 18(13): 4674-86, 2010 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20570526
8.
A Highly Selective Rho-Kinase Inhibitor (ITRI-E-212) Potentially Treats Glaucoma Upon Topical Administration With Low Incidence of Ocular Hyperemia.
Invest Ophthalmol Vis Sci
; 60(2): 624-633, 2019 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30735565
9.
Synthesis of 1-substituted 3-pyridinylmethylidenylindolin-2-ones and 1-substituted 3-quinolinylmethylidenylindolin-2-ones as the enhancers of ATRA-induced differentiation in HL-60 cells.
Bioorg Med Chem
; 16(8): 4222-32, 2008 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18346898
10.
Investigation of anti-leukemia molecular mechanism of ITR-284, a carboxamide analog, in leukemia cells and its effects in WEHI-3 leukemia mice.
Biochem Pharmacol
; 79(3): 389-98, 2010 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19765549
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