Detalles de la búsqueda
1.
Hypoxia-induced ELF3 promotes tumor angiogenesis through IGF1/IGF1R.
EMBO Rep
; 23(8): e52977, 2022 08 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35695065
2.
Di-indenopyridines as topoisomerase II-selective anticancer agents: Design, synthesis, and structure-activity relationships.
Bioorg Med Chem
; 91: 117403, 2023 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37418826
3.
Design, synthesis, and biological evaluation of novel HSP27 inhibitors to sensitize lung cancer cells to clinically available anticancer agents.
Bioorg Chem
; 130: 106260, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36410114
4.
Topoisomerase IIα inhibitory and antiproliferative activity of dihydroxylated 2,6-diphenyl-4-fluorophenylpyridines: Design, synthesis, and structure-activity relationships.
Bioorg Med Chem Lett
; 60: 128606, 2022 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35123005
5.
4-Flourophenyl-substituted 5H-indeno[1,2-b]pyridinols with enhanced topoisomerase IIα inhibitory activity: Synthesis, biological evaluation, and structure-activity relationships.
Bioorg Chem
; 116: 105349, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34536927
6.
AK-I-190, a New Catalytic Inhibitor of Topoisomerase II with Anti-Proliferative and Pro-Apoptotic Activity on Androgen-Negative Prostate Cancer Cells.
Int J Mol Sci
; 22(20)2021 Oct 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34681904
7.
Synthesis and evaluation of 7-(3-aminopropyloxy)-substituted flavone analogue as a topoisomerase IIα catalytic inhibitor and its sensitizing effect to enzalutamide in castration-resistant prostate cancer cells.
Eur J Med Chem
; 246: 114999, 2023 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36493620
8.
Interrupting specific hydrogen bonds between ELF3 and MED23 as an alternative drug resistance-free strategy for HER2-overexpressing cancers.
J Adv Res
; 47: 173-187, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35963541
9.
Identification of new halogen-containing 2,4-diphenyl indenopyridin-5-one derivative as a boosting agent for the anticancer responses of clinically available topoisomerase inhibitors.
Eur J Med Chem
; 227: 113916, 2022 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34678573
10.
Discovery of a 2,4-diphenyl-5,6-dihydrobenzo(h)quinolin-8-amine derivative as a novel DNA intercalating topoisomerase IIα poison.
Eur J Med Chem
; 226: 113860, 2021 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34597897
11.
Submandibular Push Exercise Using Visual Feedback from a Pressure Sensor in Patients with Swallowing Difficulties: A Pilot Study.
Healthcare (Basel)
; 9(4)2021 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33916285
12.
Identification of Indicators for Preterm Birth Using Retinoid Metabolites.
Metabolites
; 11(7)2021 Jul 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34357337
13.
Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 Dimers.
Pharmaceutics
; 13(5)2021 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-33925114
14.
Specific Roles of HSP27 S15 Phosphorylation Augmenting the Nuclear Function of HER2 to Promote Trastuzumab Resistance.
Cancers (Basel)
; 12(6)2020 Jun 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32545363
15.
Field-based rational design of p300 histone acetyltransferase inhibitor and systematic evaluation as an anti-fibrotic agent.
Chem Commun (Camb)
; 56(68): 9795-9798, 2020 Aug 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32701101
16.
Effect of the submandibular push exercise using visual feedback from pressure sensor: an electromyography study.
Sci Rep
; 10(1): 11772, 2020 07 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-32678239
17.
Plumbagin Suppresses Pulmonary Fibrosis via Inhibition of p300 Histone Acetyltransferase Activity.
J Med Food
; 23(6): 633-640, 2020 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-32311286
18.
Recent therapeutic trends and promising targets in triple negative breast cancer.
Pharmacol Ther
; 199: 30-57, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30825473
19.
A chromenone analog as an ATP-competitive, DNA non-intercalative topoisomerase II catalytic inhibitor with preferences toward the alpha isoform.
Chem Commun (Camb)
; 55(85): 12857-12860, 2019 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31598611
20.
Discovery and Biological Evaluations of Halogenated 2,4-Diphenyl Indeno[1,2-b]pyridinol Derivatives as Potent Topoisomerase IIα-Targeted Chemotherapeutic Agents for Breast Cancer.
J Med Chem
; 62(17): 8194-8234, 2019 09 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31398033