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1.
Discovery of an Irreversible and Cell-Active BCL6 Inhibitor Selectively Targeting Cys53 Located at the Protein-Protein Interaction Interface.
Biochemistry
; 57(8): 1369-1379, 2018 02 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-29293322
2.
Synthesis, SAR study, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase (FAAH) inhibitors.
Bioorg Med Chem
; 21(1): 28-41, 2013 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23218778
3.
Cryo-EM Structure of K+-Bound hERG Channel Complexed with the Blocker Astemizole.
Structure
; 29(3): 203-212.e4, 2021 03 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33450182
4.
LSD1 enzyme inhibitor TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models.
Sci Adv
; 7(11)2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33712455
5.
T-448, a specific inhibitor of LSD1 enzyme activity, improves learning function without causing thrombocytopenia in mice.
Neuropsychopharmacology
; 44(8): 1505-1512, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30580376
6.
Structure-Based Approach for the Discovery of Pyrrolo[3,2-d]pyrimidine-Based EGFR T790M/L858R Mutant Inhibitors.
ACS Med Chem Lett
; 4(2): 201-5, 2013 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900643
7.
Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins.
J Med Chem
; 56(23): 9635-45, 2013 Dec 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-24215352
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