Detalles de la búsqueda
1.
Racemization of the substrate and product by serine palmitoyltransferase from Sphingobacterium multivorum yields two enantiomers of the product from d-serine.
J Biol Chem
; 300(3): 105728, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38325740
2.
Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.
Biochem Biophys Res Commun
; 525(2): 348-353, 2020 04 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-32093886
3.
Kanechlor 500-mediated changes in serum and hepatic thyroxine levels primarily occur in a transthyretin-unrelated manner.
J Appl Toxicol
; 39(12): 1701-1709, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31498458
4.
Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation.
J Pharmacol Exp Ther
; 361(2): 199-208, 2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28228532
5.
Expression of UGT1A subfamily in rat brain.
Biopharm Drug Dispos
; 37(5): 314-9, 2016 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-27061716
6.
Alteration of the function of the UDP-glucuronosyltransferase 1A subfamily by cytochrome P450 3A4: different susceptibility for UGT isoforms and UGT1A1/7 variants.
Drug Metab Dispos
; 42(2): 229-38, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24255116
7.
Mammalian cytochrome P450-dependent metabolism of polychlorinated dibenzo-p-dioxins and coplanar polychlorinated biphenyls.
Int J Mol Sci
; 15(8): 14044-57, 2014 Aug 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-25123135
8.
Comparative study on 2,2',4,5,5'-pentachlorobiphenyl-mediated decrease in serum thyroxine level between C57BL/6 and its transthyretin-deficient mice.
Toxicol Appl Pharmacol
; 263(3): 323-9, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22800508
9.
8-Prenylnaringenin tissue distribution and pharmacokinetics in mice and its binding to human serum albumin and cellular uptake in human embryonic kidney cells.
Food Sci Nutr
; 10(4): 1070-1080, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35432956
10.
Metabolism of the c-Fos/activator protein-1 inhibitor T-5224 by multiple human UDP-glucuronosyltransferase isoforms.
Drug Metab Dispos
; 39(5): 803-13, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21346002
11.
Epicatechin gallate and epigallocatechin gallate are potent inhibitors of human arylacetamide deacetylase.
Drug Metab Pharmacokinet
; 39: 100397, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-34171773
12.
Pharmacokinetics and metabolism of cinnamic acid derivatives and flavonoids after oral administration of Brazilian green propolis in humans.
Food Funct
; 12(6): 2520-2530, 2021 Mar 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-33688872
13.
A possible mechanism for the decrease in serum thyroxine level by a 2,3,7,8-tetrachlorodibenzo-p-dioxin-like polychlorinated biphenyl congener, 3,3',4,4',5-pentachlorobiphenyl in mice.
Drug Metab Dispos
; 38(1): 150-6, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19786508
14.
Nutritional status affects fluvastatin-induced hepatotoxicity and myopathy in rats.
Drug Metab Dispos
; 38(10): 1655-64, 2010 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20587623
15.
Metabolism of mono- and dichloro-dibenzo-p-dioxins by Phanerochaete chrysosporium cytochromes P450.
Appl Microbiol Biotechnol
; 86(2): 773-80, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20201136
16.
Enzymatic properties of cytochrome P450 catalyzing 3'-hydroxylation of naringenin from the white-rot fungus Phanerochaete chrysosporium.
Biochem Biophys Res Commun
; 387(1): 103-8, 2009 Sep 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-19576179
17.
4-Hydroxy-2,2',3,4',5,5',6-heptachlorobiphenyl-mediated decrease in serum thyroxine level in mice occurs through increase in accumulation of thyroxine in the liver.
Drug Metab Dispos
; 37(10): 2095-102, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19589873
18.
Quantitative analysis of UDP-glucuronosyltransferase (UGT) 1A and UGT2B expression levels in human livers.
Drug Metab Dispos
; 37(8): 1759-68, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19439486
19.
Inhibitory effects of adenine nucleotides and related substances on UDP-glucuronosyltransferase: structure-effect relationships and evidence for an allosteric mechanism.
Biochim Biophys Acta
; 1770(11): 1557-66, 2007 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-17764847
20.
Ontogenic isoform switching of UDP-glucuronosyltransferase family 1 in rat liver.
Biochem Biophys Res Commun
; 377(3): 815-9, 2008 Dec 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-18938141