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1.
Renal tubular transporter-mediated interactions between mirogabalin and cimetidine in rats.
Xenobiotica
; 53(2): 114-122, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36715563
2.
Curcumin as an In Vivo Selective Intestinal Breast Cancer Resistance Protein Inhibitor in Cynomolgus Monkeys.
Drug Metab Dispos
; 46(5): 667-679, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29358184
3.
Evaluation of the usefulness of breast cancer resistance protein (BCRP) knockout mice and BCRP inhibitor-treated monkeys to estimate the clinical impact of BCRP modulation on the pharmacokinetics of BCRP substrates.
Pharm Res
; 32(5): 1634-47, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25380981
4.
Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition.
Drug Metab Dispos
; 42(4): 520-8, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24459178
5.
Integrated approach of in vivo and in vitro evaluation of the involvement of hepatic uptake organic anion transporters in the drug disposition in rats using rifampicin as an inhibitor.
Drug Metab Dispos
; 41(7): 1442-9, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23640987
6.
Recent Advances in the Gastrointestinal Complex in Vitro Model for ADME Studies.
Pharmaceutics
; 16(1)2023 Dec 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-38258048
7.
Gutsy science: In vitro systems of the human intestine to model oral drug disposition.
Pharmacol Ther
; 230: 107962, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34478775
8.
Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system.
Sci Rep
; 11(1): 21356, 2021 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34725352
9.
Microphysiological system modeling of ochratoxin A-associated nephrotoxicity.
Toxicology
; 444: 152582, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32905824
10.
An Improved Vascularized, Dual-Channel Microphysiological System Facilitates Modeling of Proximal Tubular Solute Secretion.
ACS Pharmacol Transl Sci
; 3(3): 496-508, 2020 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32566915
11.
A Potent Blood-Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model.
Mol Cancer Ther
; 19(2): 375-383, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31727689
12.
Discovery of Novel Pyrido-pyridazinone Derivatives as FER Tyrosine Kinase Inhibitors with Antitumor Activity.
ACS Med Chem Lett
; 10(5): 737-742, 2019 May 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31097992
13.
Liver-selective distribution in rats supports the importance of active uptake into the liver via organic anion transporting polypeptides (OATPs) in humans.
Drug Metab Pharmacokinet
; 30(5): 334-40, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26403085
14.
Involvement of rat organic anion transporter 3 in the uptake of an organic herbicide, 2,4-dichlorophenoxyacetate, by the isolated rat choroid plexus.
J Pharm Sci
; 93(11): 2724-32, 2004 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-15389674
15.
Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir.
Mol Pharmacol
; 71(2): 619-27, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17110501
16.
A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters.
J Pharmacol Exp Ther
; 315(1): 337-45, 2005 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-16006492
17.
The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules.
J Am Soc Nephrol
; 15(8): 2012-22, 2004 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15284287
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