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1.
Nonclinical Cardiovascular Assessment of the Soluble Guanylate Cyclase Stimulator Vericiguat.
J Pharmacol Exp Ther
; 386(1): 26-34, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37068911
2.
Combining an in silico proarrhythmic risk assay with a tPKPD model to predict QTc interval prolongation in the anesthetized guinea pig assay.
Toxicol Appl Pharmacol
; 390: 114883, 2020 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31981640
3.
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.
Toxicol Appl Pharmacol
; 394: 114961, 2020 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32209365
4.
Can Galactose Be Converted to Glucose in HepG2 Cells? Improving the in Vitro Mitochondrial Toxicity Assay for the Assessment of Drug Induced Liver Injury.
Chem Res Toxicol
; 32(8): 1528-1544, 2019 08 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-31271030
5.
Interaction between amiodarone and hepatitis-C virus nucleotide inhibitors in human induced pluripotent stem cell-derived cardiomyocytes and HEK-293 Cav1.2 over-expressing cells.
Toxicol Appl Pharmacol
; 308: 66-76, 2016 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27520758
6.
Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].
Toxicol Appl Pharmacol
; 395: 114983, 2020 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32247767
7.
Comparative assessment of Ca2+ oscillations in 2- and 3-dimensional hiPSC derived and isolated cortical neuronal networks.
J Pharmacol Toxicol Methods
; 123: 107281, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37390871
8.
FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for in vitro pharmacology.
APL Bioeng
; 7(4): 046113, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-38046544
9.
Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
Sci Rep
; 10(1): 11884, 2020 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32665705
10.
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
Sci Rep
; 10(1): 5627, 2020 03 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-32221320
11.
Application of PatchXpress planar patch clamp technology to the screening of new drug candidates for cardiac KCNQ1/KCNE1 (I Ks) activity.
Assay Drug Dev Technol
; 5(5): 617-27, 2007 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17939752
12.
Cardiac drug-drug interaction between HCV-NS5B pronucleotide inhibitors and amiodarone is determined by their specific diastereochemistry.
Sci Rep
; 7: 44820, 2017 03 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-28327633
13.
A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm.
J Biomol Screen
; 21(1): 1-11, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26170255
14.
Generation and characterization of a cell line with inducible expression of Ca(v)3.2 (T-type) channels.
Assay Drug Dev Technol
; 1(5): 637-45, 2003 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15090236
15.
Interaction of the BKCa channel gating ring with dendrotoxins.
Channels (Austin)
; 8(5): 421-32, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25483585
16.
The anesthetized guinea pig: an effective early cardiovascular derisking and lead optimization model.
J Pharmacol Toxicol Methods
; 68(1): 137-49, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23649000
17.
Assessing use-dependent inhibition of the cardiac Na(+/-) current (I(Na)) in the PatchXpress automated patch clamp.
J Pharmacol Toxicol Methods
; 62(2): 107-18, 2010.
Artículo
en Inglés
| MEDLINE | ID: mdl-20601018
18.
Optimization of Ca(v)1.2 screening with an automated planar patch clamp platform.
J Pharmacol Toxicol Methods
; 59(2): 62-72, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19367686
19.
Modeling of the adrenergic response of the human IKs current (hKCNQ1/hKCNE1) stably expressed in HEK-293 cells.
Am J Physiol Heart Circ Physiol
; 295(5): H1867-81, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18757482
20.
State-dependent inhibition of L-type calcium channels: cell-based assay in high-throughput format.
Anal Biochem
; 327(1): 74-81, 2004 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15033513
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