Detalles de la búsqueda
1.
Novel Screening System for Biliary Excretion of Drugs Using Human Cholangiocyte Organoid Monolayers with Directional Drug Transport.
Biol Pharm Bull
; 47(2): 427-433, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38369341
2.
Formation of functional, extended bile canaliculi, and increased bile acid production in sandwich-cultured human cryopreserved hepatocytes using commercially available culture medium.
Arch Toxicol
; 2024 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38753187
3.
Label-Free Evaluation of Maturation and Hepatotoxicity of Human iPSC-Derived Hepatocytes Using Hyperspectral Raman Imaging.
Anal Chem
; 95(24): 9252-9262, 2023 06 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37293770
4.
Directional Drug Transport through Membrane-Supported Monolayers of Human Liver-Derived Cell Lines.
Biol Pharm Bull
; 45(1): 150-153, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-34980776
5.
Inhibitory effect of hybrid liposomes on the growth of liver cancer stem cells.
Biochem Biophys Res Commun
; 509(1): 268-274, 2019 01 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-30583860
6.
Prediction of Human Hepatic Clearance for Cytochrome P450 Substrates via a New Culture Method Using the Collagen Vitrigel Membrane Chamber and Fresh Hepatocytes Isolated from Liver Humanized Mice.
Biol Pharm Bull
; 42(3): 348-353, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30828066
7.
Late stage definitive endodermal differentiation can be defined by Daf1 expression.
BMC Dev Biol
; 16(1): 19, 2016 05 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-27245320
8.
Design, synthesis, and evaluation of Trolox-conjugated amyloid-ß C-terminal peptides for therapeutic intervention in an in vitro model of Alzheimer's disease.
Bioorg Med Chem
; 24(18): 4138-4143, 2016 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27407032
9.
Increase of ß2-integrin on adhesion of THP-1 cells to collagen vitrigel membrane.
Biosci Biotechnol Biochem
; 80(11): 2271-2276, 2016 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-27379801
10.
Inflammatory cytokines promote the retrodifferentiation of tumor-derived hepatocyte-like cells to progenitor cells.
Hepatology
; 60(6): 2077-90, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25098666
11.
Selective elimination of tumorigenic cells from mixed culture of normal and tumorigenic cells using hybrid liposomes aimed at realizing of cell therapy.
Cytotechnology
; 76(2): 247-258, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38495296
12.
Human intestinal organoid-derived PDGFRα + mesenchymal stroma enables proliferation and maintenance of LGR4 + epithelial stem cells.
Stem Cell Res Ther
; 15(1): 16, 2024 01 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38229108
13.
Gene expression phenotypic models that predict the activity of oncogenic pathways.
Nat Genet
; 34(2): 226-30, 2003 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12754511
14.
[Developing and standardizing experimental protocols using human iPS-derived cells to predict adverse drug reactions in pre-clinical safety studies].
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku
; (131): 25-34, 2013.
Artículo
en Japonés
| MEDLINE | ID: mdl-24340667
15.
Construction of extended and functional bile canaliculi using long-term sandwich-cultured cryopreserved human hepatocytes and the application of hepatocytes for predicting the biliary excretion of pharmaceutical and food-related compounds.
J Toxicol Sci
; 48(5): 251-261, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37121740
16.
Usefulness of a humanized tricellular static transwell blood-brain barrier model as a microphysiological system for drug development applications. - A case study based on the benchmark evaluations of blood-brain barrier microphysiological system.
Regen Ther
; 22: 192-202, 2023 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-36891355
17.
Consideration of Commercially Available Hepatocytes as Cell Sources for Liver-Microphysiological Systems by Comparing Liver Characteristics.
Pharmaceutics
; 15(1)2022 Dec 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-36678684
18.
A physiologically based kinetic modeling of ethyl tert-butyl ether in humans-An illustrative application of quantitative structure-property relationship and Monte Carlo simulation.
J Toxicol Sci
; 47(2): 77-87, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35110473
19.
Label-free chemical imaging of cytochrome P450 activity by Raman microscopy.
Commun Biol
; 5(1): 778, 2022 08 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-35995965
20.
Construction of a culture protocol for functional bile canaliculi formation to apply human iPS cell-derived hepatocytes for cholestasis evaluation.
Sci Rep
; 12(1): 15192, 2022 09 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36071090