Detalles de la búsqueda
1.
Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer's Disease Treatment.
Int J Mol Sci
; 24(11)2023 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37298693
2.
The Proof-of-Concept of MBA121, a Tacrine-Ferulic Acid Hybrid, for Alzheimer's Disease Therapy.
Int J Mol Sci
; 24(15)2023 Jul 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-37569630
3.
Benzochromenopyrimidines: Synthesis, Antiproliferative Activity against Colorectal Cancer and Physicochemical Properties.
Molecules
; 27(22)2022 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36431976
4.
Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation.
Molecules
; 28(1)2022 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36615267
5.
Tacrines as Therapeutic Agents for Alzheimer's Disease. V. Recent Developments.
Chem Rec
; 21(1): 162-174, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-33169934
6.
Synthesis and biological assessment of new pyrimidopyrimidines as inhibitors of breast cancer resistance protein (ABCG2).
Bioorg Chem
; 116: 105326, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34536930
7.
Propargylamine-derived multi-target directed ligands for Alzheimer's disease therapy.
Bioorg Med Chem Lett
; 30(3): 126880, 2020 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31864798
8.
Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives.
Int J Mol Sci
; 21(20)2020 Oct 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-33081112
9.
Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy.
Int J Mol Sci
; 21(11)2020 May 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-32486316
10.
Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer's Disease Therapy.
Molecules
; 25(14)2020 Jul 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-32668671
11.
Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels.
Molecules
; 25(6)2020 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32183349
12.
Multi-target 1,4-dihydropyridines showing calcium channel blockade and antioxidant capacity for Alzheimer's disease therapy.
Bioorg Chem
; 91: 103205, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31446330
13.
Synthesis, antioxidant and Aß anti-aggregation properties of new ferulic, caffeic and lipoic acid derivatives obtained by the Ugi four-component reaction.
Bioorg Chem
; 85: 221-228, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30640071
14.
Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer's disease therapy.
J Enzyme Inhib Med Chem
; 34(1): 479-489, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30712420
15.
Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy.
J Enzyme Inhib Med Chem
; 34(1): 163-170, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30482062
16.
Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases.
Angew Chem Int Ed Engl
; 56(41): 12765-12769, 2017 10 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28861918
17.
Imidazopyranotacrines as Non-Hepatotoxic, Selective Acetylcholinesterase Inhibitors, and Antioxidant Agents for Alzheimer's Disease Therapy.
Molecules
; 21(4): 400, 2016 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-27023499
18.
Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease.
Molecules
; 21(5)2016 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-27187348
19.
Quinolone-benzylpiperidine derivatives as novel acetylcholinesterase inhibitor and antioxidant hybrids for Alzheimer disease.
Bioorg Med Chem
; 22(8): 2496-507, 2014 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24657052
20.
Calcium channel blockers' contribution to overcoming Current drug discovery challenges in Alzheimer's disease.
Expert Opin Drug Discov
; 19(1): 21-32, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-37800853