Búsqueda | Biblioteca Virtual en Salud

1.

Identification and Preliminary Structure-Activity Relationship Studies of 1,5-Dihydrobenzo[e][1,4]oxazepin-2(3H)-ones That Induce Differentiation of Acute Myeloid Leukemia Cells In Vitro.

Josa-Culleré, Laia; Cogswell, Thomas J; Georgiou, Irene; Jay-Smith, Morgan; Jackson, Thomas R; Bataille, Carole J R; Davies, Stephen G; Vyas, Paresh; Milne, Thomas A; Wynne, Graham M; Russell, Angela J.

Molecules ; 26(21)2021 Nov 02.

Artículo en Inglés | MEDLINE | ID: mdl-34771052

2.

Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines.

Josa-Culleré, Laia; Galan, Sébastien R G; Cogswell, Thomas J; Jackson, Thomas R; Jay-Smith, Morgan; Mola, Laura; Greaves, Christopher R; Carter, Tom S; Madden, Katrina S; Trott, Sophie; Zhang, Douzi; Bataille, Carole J R; Davies, Stephen G; Vyas, Paresh; Milne, Thomas A; Naylor, Alan; Wynne, Graham M; Russell, Angela J.

Eur J Med Chem ; 258: 115509, 2023 Oct 05.

Artículo en Inglés | MEDLINE | ID: mdl-37343464

3.

A tubulin binding molecule drives differentiation of acute myeloid leukemia cells.

Jackson, Thomas R; Vuorinen, Aini; Josa-Culleré, Laia; Madden, Katrina S; Conole, Daniel; Cogswell, Thomas J; Wilkinson, Isabel V L; Kettyle, Laura M; Zhang, Douzi; O'Mahony, Alison; Gracias, Deanne; McCall, Lorna; Westwood, Robert; Terstappen, Georg C; Davies, Stephen G; Tate, Edward W; Wynne, Graham M; Vyas, Paresh; Russell, Angela J; Milne, Thomas A.

iScience ; 25(8): 104787, 2022 Aug 19.

Artículo en Inglés | MEDLINE | ID: mdl-35992086

4.

The Origin of B-cells: Human Fetal B Cell Development and Implications for the Pathogenesis of Childhood Acute Lymphoblastic Leukemia.

Jackson, Thomas R; Ling, Rebecca E; Roy, Anindita.

Front Immunol ; 12: 637975, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-33679795

5.

A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells In Vitro and Shows Antitumor Effects In Vivo.

Josa-Culleré, Laia; Madden, Katrina S; Cogswell, Thomas J; Jackson, Thomas R; Carter, Tom S; Zhang, Douzi; Trevitt, Graham; Davies, Stephen G; Vyas, Paresh; Wynne, Graham M; Milne, Thomas A; Russell, Angela J.

J Med Chem ; 64(21): 15608-15628, 2021 11 11.

Artículo en Inglés | MEDLINE | ID: mdl-34672555

6.

DNA methylation of the Oct4A enhancers in embryonal carcinoma cells after etoposide treatment is associated with alternative splicing and altered pluripotency in reversibly senescent cells.

Baryshev, Mikhail; Inashkina, Inna; Salmina, Kristine; Huna, Anda; Jackson, Thomas R; Erenpreisa, Jekaterina.

Cell Cycle ; 17(3): 362-366, 2018.

Artículo en Inglés | MEDLINE | ID: mdl-29372665

7.

MultiElec: A MATLAB Based Application for MEA Data Analysis.

Georgiadis, Vassilis; Stephanou, Anastasis; Townsend, Paul A; Jackson, Thomas R.

PLoS One ; 10(6): e0129389, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-26076010

8.

The "virgin birth", polyploidy, and the origin of cancer.

Erenpreisa, Jekaterina; Salmina, Kristine; Huna, Anda; Jackson, Thomas R; Vazquez-Martin, Alejandro; Cragg, Mark S.

Oncoscience ; 2(1): 3-14, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-25821840

9.

Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide.

Huna, Anda; Salmina, Kristine; Erenpreisa, Jekaterina; Vazquez-Martin, Alejandro; Krigerts, Jekabs; Inashkina, Inna; Gerashchenko, Bogdan I; Townsend, Paul A; Cragg, Mark S; Jackson, Thomas R.

Cell Cycle ; 14(18): 2969-84, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-26102294

10.

Annexin A3 is a mammary marker and a potential neoplastic breast cell therapeutic target.

Zeidan, Bashar; Jackson, Thomas R; Larkin, Samantha E T; Cutress, Ramsey I; Coulton, Gary R; Ashton-Key, Margaret; Murray, Nick; Packham, Graham; Gorgoulis, Vassilis; Garbis, Spiros D; Townsend, Paul A.

Oncotarget ; 6(25): 21421-7, 2015 Aug 28.

Artículo en Inglés | MEDLINE | ID: mdl-26093083

11.

China's one-child family policy.

Jackson, Thomas R.

N Engl J Med ; 354(8): 877; author reply 877, 2006 Feb 23.

Artículo en Inglés | MEDLINE | ID: mdl-16495406

12.

DNA damage causes TP53-dependent coupling of self-renewal and senescence pathways in embryonal carcinoma cells.

Jackson, Thomas R; Salmina, Kristine; Huna, Anda; Inashkina, Inna; Jankevics, Eriks; Riekstina, Una; Kalnina, Zane; Ivanov, Andrey; Townsend, Paul A; Cragg, Mark S; Erenpreisa, Jekaterina.

Cell Cycle ; 12(3): 430-41, 2013 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-23287532

13.

Macroautophagy-aided elimination of chromatin: sorting of waste, sorting of fate?

Erenpreisa, Jekaterina; Huna, Anda; Salmina, Kristine; Jackson, Thomas R; Cragg, Mark S.

Autophagy ; 8(12): 1877-81, 2012 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-22935563

14.

Study results from the Clinical Trials Network's first 10 years: where do they lead?

Wells, Elizabeth A; Saxon, Andrew J; Calsyn, Donald A; Jackson, Thomas R; Donovan, Dennis M.

J Subst Abuse Treat ; 38 Suppl 1: S14-30, 2010 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-20307792

15.

Boronate affinity saccharide electrophoresis: a novel carbohydrate analysis tool.

Jackson, Thomas R; Springall, Jeremy S; Rogalle, Damien; Masumoto, Naoko; Ching Li, Hung; D'Hooge, François; Perera, Semali P; Jenkins, A Toby A; James, Tony D; Fossey, John S; van den Elsen, Jean M H.

Electrophoresis ; 29(20): 4185-91, 2008 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-18925583

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