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1.
Differential role of P-glycoprotein and breast cancer resistance protein in drug distribution into brain, CSF and peripheral nerve tissues in rats.
Xenobiotica
; 45(6): 547-55, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25539457
2.
Use of uptake intrinsic clearance from attached rat hepatocytes to predict hepatic clearance for poorly permeable compounds.
Xenobiotica
; 42(9): 830-40, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22439758
3.
In vitro and in vivo pharmacokinetic characterizations of AMG 900, an orally bioavailable small molecule inhibitor of aurora kinases.
Xenobiotica
; 41(5): 400-8, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21294625
4.
Relationship between passive permeability, efflux, and predictability of clearance from in vitro metabolic intrinsic clearance.
Drug Metab Dispos
; 38(2): 223-31, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19875499
5.
Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant alpha4beta2 nicotinic acetylcholine receptor potentiators.
Bioorg Med Chem Lett
; 18(19): 5209-12, 2008 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18789861
6.
Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2.
Bioorg Med Chem Lett
; 18(15): 4267-74, 2008 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18640038
7.
Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain.
J Med Chem
; 54(13): 4427-45, 2011 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-21634377
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