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1.
Combined inhibition of CCR2 and ACE provides added protection against progression of diabetic nephropathy in Nos3-deficient mice.
Am J Physiol Renal Physiol
; 317(6): F1439-F1449, 2019 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31566438
2.
Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers.
Clin Immunol
; 191: 10-20, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29518577
3.
Preclinical to clinical translation of tofacitinib, a Janus kinase inhibitor, in rheumatoid arthritis.
J Pharmacol Exp Ther
; 348(1): 165-73, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24218541
4.
Mechanistic investigations of test article-induced pancreatic toxicity at the endocrine-exocrine interface in the rat.
Toxicol Pathol
; 42(1): 229-42, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24226507
5.
JAK inhibition with tofacitinib suppresses arthritic joint structural damage through decreased RANKL production.
Arthritis Rheum
; 64(11): 3531-42, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22899318
6.
Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).
J Immunol
; 186(7): 4234-43, 2011 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21383241
7.
Characterization of the KRN cell transfer model of rheumatoid arthritis (KRN-CTM), a chronic yet synchronized version of the K/BxN mouse.
Am J Pathol
; 177(3): 1388-96, 2010 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-20696780
8.
Janus kinase inhibitors for the treatment of rheumatoid arthritis demonstrate similar profiles of in vitro cytokine receptor inhibition.
Pharmacol Res Perspect
; 7(6): e00537, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31832202
9.
PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor.
ACS Chem Biol
; 14(6): 1235-1242, 2019 06 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31082193
10.
PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism.
Cancer Res
; 64(15): 5471-80, 2004 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15289357
11.
Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis.
J Inflamm (Lond)
; 7: 41, 2010 Aug 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-20701804
12.
Hematopoietic stimulation by a dipeptidyl peptidase inhibitor reveals a novel regulatory mechanism and therapeutic treatment for blood cell deficiencies.
Blood
; 102(5): 1641-8, 2003 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12738665
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