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1.
Detection of glutathione conjugates of amiodarone and its reactive diquinone metabolites in rat bile using mass spectrometry tools.
Rapid Commun Mass Spectrom
; 30(10): 1242-1248, 2016 05 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-28328020
2.
Metabolite identification studies on amiodarone in in vitro (rat liver microsomes, rat and human liver S9 fractions) and in vivo (rat feces, urine, plasma) matrices by using liquid chromatography with high-resolution mass spectrometry and multiple-stage mass spectrometry: characterization of the diquinone metabolite supposedly responsible for the drug's hepatotoxicity.
Rapid Commun Mass Spectrom
; 28(4): 311-31, 2014 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-24395499
3.
Characterization of forced degradation products of torasemide through MS tools and explanation of unusual losses observed during mass fragmentation of drug and degradation products through density functional theory.
J Pharm Biomed Anal
; 145: 209-218, 2017 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-28666167
4.
Molecular insight into atypical instability behavior of fixed-dose combination containing amlodipine besylate and losartan potassium.
J Pharm Biomed Anal
; 136: 66-80, 2017 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-28064090
5.
Identification of stable and reactive metabolite(s) of nelfinavir in human liver microsomes and rCYP3A4.
J Pharm Biomed Anal
; 118: 214-227, 2016 Jan 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-26571359
6.
Explanation through density functional theory of the unanticipated loss of CO2 and differences in mass fragmentation profiles of ritonavir and its rCYP3A4-mediated metabolites.
J Mass Spectrom
; 49(6): 452-67, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24913398
7.
Critical practical aspects in the application of liquid chromatography-mass spectrometric studies for the characterization of impurities and degradation products.
J Pharm Biomed Anal
; 87: 191-217, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23706957
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