Detalles de la búsqueda
1.
Application of 18ß-glycyrrhetinic acid in the structural modification of natural products: a review.
Mol Divers
; 2024 Apr 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-38683490
2.
Synthesis and Antimicrobial Activity Evaluation of Pyridine Derivatives Containing Imidazo[2,1-b][1,3,4]Thiadiazole Moiety.
Chem Biodivers
; 21(4): e202400135, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38425248
3.
Synthesis of amide derivatives containing the imidazole moiety and evaluation of their anti-cardiac fibrosis activity.
Arch Pharm (Weinheim)
; : e2400131, 2024 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38678538
4.
Synthesis of and anti-fibrotic effect of pyrazole derivative J-1048: Inhibition of ALK5 as a novel approach to liver fibrosis targeting inflammation.
Bioorg Chem
; 139: 106723, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37459824
5.
Synthesis and Antibacterial Activity Evaluation of Imidazole Derivatives Containing 6-Methylpyridine Moiety.
Chem Biodivers
; 20(5): e202300105, 2023 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-36945745
6.
Synthesis and antimicrobial activity evaluation of pyrazole derivatives containing the imidazo[2,1-b][1,3,4]thiadiazole moiety.
Arch Pharm (Weinheim)
; 356(8): e2300110, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37328442
7.
The in vitro and in vivo study of a pyrazole derivative, J-1063, as a novel anti-liver fibrosis agent: Synthesis, biological evaluation, and mechanistic analysis.
Bioorg Chem
; 122: 105715, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35279552
8.
New role of sertraline against Toxoplasma gondii-induced depression-like behaviours in mice.
Parasite Immunol
; 43(12): e12893, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34637545
9.
Usnic acid suppresses cervical cancer cell proliferation by inhibiting PD-L1 expression and enhancing T-lymphocyte tumor-killing activity.
Phytother Res
; 35(7): 3916-3935, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-33970512
10.
Panaxadiol inhibits programmed cell death-ligand 1 expression and tumour proliferation via hypoxia-inducible factor (HIF)-1α and STAT3 in human colon cancer cells.
Pharmacol Res
; 155: 104727, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32113874
11.
Synthesis and evaluation of the HIF-1α inhibitory activity of 3(5)-substituted-4-(quinolin-4-yl)- and 4-(2-phenylpyridin-4-yl)pyrazoles as inhibitors of ALK5.
Bioorg Med Chem Lett
; 30(2): 126822, 2020 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31810777
12.
Convallatoxin protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB signaling through activation of PPARγ.
Pharmacol Res
; 147: 104355, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31386886
13.
Synthesis and biological evaluation of novel benzo[c][1,2,5]thiadiazol-5-yl and thieno[3,2-c]- pyridin-2-yl imidazole derivatives as ALK5 inhibitors.
Bioorg Med Chem Lett
; 29(16): 2070-2075, 2019 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31303386
14.
Synthesis and Evaluation of 3-Substituted-4-(quinoxalin-6-yl) Pyrazoles as TGF-ß Type I Receptor Kinase Inhibitors.
Molecules
; 23(12)2018 Dec 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-30572609
15.
Novel oral transforming growth factor-ß signaling inhibitor EW-7197 eradicates CML-initiating cells.
Cancer Sci
; 107(2): 140-8, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26583567
16.
Synthesis and biological evaluation of 5-(fluoro-substituted-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)imidazoles as inhibitors of transforming growth factor-ß type I receptor kinase.
Bioorg Med Chem Lett
; 25(22): 5228-31, 2015 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26483198
17.
4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5(3)-(6-methylpyridin-2-yl)imidazole and -pyrazole derivatives as potent and selective inhibitors of transforming growth factor-ß type I receptor kinase.
Bioorg Med Chem
; 22(9): 2724-32, 2014 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24704197
18.
Single-port thoracoscopic sympathicotomy using a double-lumen electrocautery tube and cautery hook for primary palmar hyperhidrosis: a randomized controlled trial.
Thorac Cardiovasc Surg
; 62(5): 439-44, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23475800
19.
Brazilin-7-acetate, a novel potential drug of Parkinson's disease, hinders the formation of α-synuclein fibril, mitigates cytotoxicity, and decreases oxidative stress.
Eur J Med Chem
; 264: 115965, 2024 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38056304
20.
Synthesis and Evaluation of Imidazole Derivatives Bearing Imidazo[2,1-b] [1,3,4]thiadiazole Moiety as Antibacterial Agents.
Med Chem
; 20(1): 40-51, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-37767798