Detalles de la búsqueda
1.
Development and verification of a full physiologically-based pharmacokinetic model for sublingual buprenorphine in healthy adult volunteers that accounts for nonlinear bioavailability.
Drug Metab Dispos
; 2024 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38769016
2.
Predictive Performance of Physiologically Based Pharmacokinetic Modelling of Beta-Lactam Antibiotic Concentrations in Adipose, Bone, and Muscle Tissues.
Drug Metab Dispos
; 51(4): 499-508, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36639242
3.
Use of Developmental Midazolam and 1-Hydroxymidazolam Data with Pediatric Physiologically Based Modeling to Assess Cytochrome P450 3A4 and Uridine Diphosphate Glucuronosyl Transferase 2B4 Ontogeny In Vivo.
Drug Metab Dispos
; 51(8): 1035-1045, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37169511
4.
Use of a physiologically based pharmacokinetic-pharmacodynamic model for initial dose prediction and escalation during a paediatric clinical trial.
Br J Clin Pharmacol
; 87(3): 1378-1389, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32822519
5.
Teicoplanin physiologically based pharmacokinetic modeling offers a quantitative assessment of a theoretical influence of serum albumin and renal function on its disposition.
Eur J Clin Pharmacol
; 77(8): 1157-1168, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-33527208
6.
Development of a physiologically based pharmacokinetic model for mefloquine and its application alongside a clinical effectiveness model to select an optimal dose for prevention of malaria in young Caucasian children.
Br J Clin Pharmacol
; 85(1): 100-113, 2019 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30198595
7.
Can Population Modelling Principles be Used to Identify Key PBPK Parameters for Paediatric Clearance Predictions? An Innovative Application of Optimal Design Theory.
Pharm Res
; 35(11): 209, 2018 Sep 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-30218393
8.
Using pharmacokinetic modelling to improve prescribing practices of intravenous aminophylline in childhood asthma exacerbations.
Pulm Pharmacol Ther
; 43: 6-11, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28108402
9.
Prediction of liver volume - a population-based approach to meta-analysis of paediatric, adult and geriatric populations - an update.
Biopharm Drug Dispos
; 38(4): 290-300, 2017 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-28084034
10.
How Does In Vivo Biliary Elimination of Drugs Change with Age? Evidence from In Vitro and Clinical Data Using a Systems Pharmacology Approach.
Drug Metab Dispos
; 44(7): 1090-8, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-26862026
11.
Development of a physiologically based pharmacokinetic model of actinomycin D in children with cancer.
Br J Clin Pharmacol
; 81(5): 989-98, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26727248
12.
Does age affect gastric emptying time? A model-based meta-analysis of data from premature neonates through to adults.
Biopharm Drug Dispos
; 36(4): 245-57, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25600493
13.
Development of physiologically based pharmacokinetic model to evaluate the relative systemic exposure to quetiapine after administration of IR and XR formulations to adults, children and adolescents.
Biopharm Drug Dispos
; 35(6): 341-52, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24797229
14.
Prediction of Pediatric Pharmacokinetics for CYP3A4 Metabolized Drugs: Comparison of the Performance of Two Hepatic Ontogeny Within a Physiologically Based Pharmacokinetic Model.
J Clin Pharmacol
; 2024 May 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38696325
15.
Forecasting Fetal Buprenorphine Exposure through Maternal-Fetal Physiologically Based Pharmacokinetic Modeling.
Pharmaceutics
; 16(3)2024 Mar 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38543269
16.
Development and Verification of a Japanese Pediatric Physiologically Based Pharmacokinetic Model with Emphasis on Drugs Eliminated by Cytochrome P450 or Renal Excretion.
J Clin Pharmacol
; 63(10): 1156-1168, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37496106
17.
Another Step Toward Qualification of Pediatric Physiologically Based Pharmacokinetic Models to Facilitate Inclusivity and Diversity in Pediatric Clinical Studies.
Clin Pharmacol Ther
; 113(3): 735-745, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36306419
18.
Physiologically Based Pharmacokinetics Modeling in the Neonatal Population-Current Advances, Challenges, and Opportunities.
Pharmaceutics
; 15(11)2023 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38004559
19.
Physiologically Based Pharmacokinetic Modelling to Predict Imatinib Exposures in Cancer Patients with Renal Dysfunction: A Case Study.
Pharmaceutics
; 15(7)2023 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37514108
20.
Incorporation and Performance Verification of Hepatic Portal Blood Flow Shunting in Minimal and Full PBPK Models of Liver Cirrhosis.
Clin Pharmacol Ther
; 114(6): 1264-1273, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37620290