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1.
QSAR Model of Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain: Incorporating P-glycoprotein Efflux as a Variable.
J Chem Inf Model
; 56(11): 2225-2233, 2016 11 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-27684523
2.
Design and synthesis of new tetrahydroquinolines derivatives as CETP inhibitors.
Bioorg Med Chem Lett
; 22(11): 3671-5, 2012 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22543028
3.
Design, synthesis and structure-activity-relationship of 1,5-tetrahydronaphthyridines as CETP inhibitors.
Bioorg Med Chem Lett
; 22(9): 3056-62, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22497761
4.
Metabolism of LY654322, a growth hormone secretagogue, to an unusual diimidazopyridine metabolite.
Drug Metab Dispos
; 39(5): 740-9, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21346003
5.
Negative allosteric modulation of alpha 5-containing GABAA receptors engenders antidepressant-like effects and selectively prevents age-associated hyperactivity in tau-depositing mice.
Psychopharmacology (Berl)
; 235(4): 1151-1161, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29374303
6.
Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABAA) Receptor Ligand That Combines Outstanding Metabolic Stability, Pharmacokinetics, and Anxiolytic Efficacy.
J Med Chem
; 59(23): 10800-10806, 2016 12 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27933953
7.
Discovery of 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia.
J Med Chem
; 58(24): 9768-72, 2015 Dec 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-26568144
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