Detalles de la búsqueda
1.
Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer's Disease Treatment.
Int J Mol Sci
; 24(11)2023 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37298693
2.
Evidence against involvement of kynurenate branch of kynurenine pathway in pathophysiology of Fuchs' dystrophy and keratoconus.
Exp Eye Res
; 216: 108959, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35074345
3.
Effects of Linkers and Substitutions on Multitarget Directed Ligands for Alzheimer's Diseases: Emerging Paradigms and Strategies.
Int J Mol Sci
; 23(11)2022 May 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-35682763
4.
Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation.
Molecules
; 28(1)2022 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36615267
5.
Comparative Antiseizure Analysis of Diverse Natural Coumarin Derivatives in Zebrafish.
Int J Mol Sci
; 22(21)2021 Oct 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34768849
6.
Structural Insights into Ligand-Receptor Interactions Involved in Biased Agonism of G-Protein Coupled Receptors.
Molecules
; 26(4)2021 Feb 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33561962
7.
Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives.
Int J Mol Sci
; 21(20)2020 Oct 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-33081112
8.
Rutamarin: Efficient Liquid-Liquid Chromatographic Isolation from Ruta graveolens L. and Evaluation of Its In Vitro and In Silico MAO-B Inhibitory Activity.
Molecules
; 25(11)2020 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32527030
9.
Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels.
Molecules
; 25(6)2020 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32183349
10.
The presence and distribution of G protein-coupled receptor 35 (GPR35) in the human cornea - Evidences from in silico gene expression analysis and immunodetection.
Exp Eye Res
; 179: 188-192, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30445046
11.
Multi-target 1,4-dihydropyridines showing calcium channel blockade and antioxidant capacity for Alzheimer's disease therapy.
Bioorg Chem
; 91: 103205, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31446330
12.
Determination of affinity and efficacy of acetylcholinesterase inhibitors using isothermal titration calorimetry.
Biochim Biophys Acta
; 1860(5): 967-974, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26586471
13.
GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts.
Int J Cancer
; 141(10): 2131-2142, 2017 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28741686
14.
The presence of kynurenine aminotransferases in the human cornea: Evidence from bioinformatics analysis of gene expression and immunohistochemical staining.
Mol Vis
; 23: 364-371, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28706436
15.
New approach in evaluation of ceramic-polymer composite bioactivity and biocompatibility.
Anal Bioanal Chem
; 409(24): 5747-5755, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28748313
16.
Molecular mechanism of action and safety of 5-(3-chlorophenyl)-4-hexyl-2,4-dihydro-3H-1,2,4-triazole-3-thione - a novel anticonvulsant drug candidate.
Int J Med Sci
; 14(8): 741-749, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28824309
17.
Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human α4ß2 and α3ß4 subtypes.
Biochim Biophys Acta
; 1848(2): 731-41, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25475645
18.
The impact of multiple sclerosis relapse treatment on migration of effector T cells--Preliminary study.
Neurol Neurochir Pol
; 50(3): 155-62, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27154441
19.
Tyrosine 308 is necessary for ligand-directed Gs protein-biased signaling of ß2-adrenoceptor.
J Biol Chem
; 289(28): 19351-63, 2014 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-24831005
20.
Agonist binding by the ß2-adrenergic receptor: an effect of receptor conformation on ligand association-dissociation characteristics.
Eur Biophys J
; 44(3): 149-63, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25726162