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1.
Gaining Insights into Key Structural Hotspots within the Allosteric Binding Pockets of Protein Kinases.
Int J Mol Sci
; 25(9)2024 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-38731943
2.
Rational design and synthesis of 2-(1H-indazol-6-yl)-1H-benzo[d]imidazole derivatives as inhibitors targeting FMS-like tyrosine kinase 3 (FLT3) and its mutants.
J Enzyme Inhib Med Chem
; 37(1): 472-486, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35067150
3.
Discovery of a Potent and Selective JNK3 Inhibitor with Neuroprotective Effect Against Amyloid ß-Induced Neurotoxicity in Primary Rat Neurons.
Int J Mol Sci
; 22(20)2021 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-34681742
4.
Design and Synthesis of a Novel PLK1 Inhibitor Scaffold Using a Hybridized 3D-QSAR Model.
Int J Mol Sci
; 22(8)2021 Apr 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33917995
5.
Discovery of N-(5-amido-2-methylphenyl)-5-methylisoxazole-3-carboxamide as dual CSF-1R/c-Kit Inhibitors with improved stability and BBB permeability.
Eur J Med Chem
; 268: 116253, 2024 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38401188
6.
Targeting the CSF-1/CSF-1R Axis: Exploring the Potential of CSF1R Inhibitors in Neurodegenerative Diseases.
J Med Chem
; 67(7): 5699-5720, 2024 Apr 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38530425
7.
Novel 1,4,5,6-tetrahydrocyclopenta[d]imidazole-5-carboxamide-based JNK3 inhibitors: Design, synthesis, molecular docking, and therapeutic potential in neurodegenerative diseases.
Eur J Med Chem
; 245(Pt 1): 114917, 2023 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36395646
8.
Carbamate JNK3 Inhibitors Show Promise as Effective Treatments for Alzheimer's Disease: In Vivo Studies on Mouse Models.
J Med Chem
; 66(9): 6372-6390, 2023 05 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37094094
9.
Discovery of novel imidazole chemotypes as isoform-selective JNK3 inhibitors for the treatment of Alzheimer's disease.
Eur J Med Chem
; 245(Pt 1): 114894, 2023 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36343411
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