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1.
Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells.
Cell
; 175(7): 1731-1743.e13, 2018 12 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-30503213
2.
Synthesis and biological evaluation of biaryl alkyl ethers as inhibitors of IDO1.
Bioorg Med Chem Lett
; 88: 129280, 2023 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37054759
3.
Development of a series of novel o-phenylenediamine-based indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.
Bioorg Med Chem Lett
; 28(4): 732-736, 2018 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29398543
4.
Deciphering CD137 (4-1BB) signaling in T-cell costimulation for translation into successful cancer immunotherapy.
Eur J Immunol
; 46(3): 513-22, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26773716
5.
Identification and optimization of a novel series of indoleamine 2,3-dioxygenase inhibitors.
Bioorg Med Chem Lett
; 27(3): 582-585, 2017 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28003141
6.
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer.
N Engl J Med
; 366(26): 2443-54, 2012 Jun 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-22658127
7.
T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes.
J Immunol
; 190(12): 6694-706, 2013 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23690480
8.
Synergy between chemotherapeutic agents and CTLA-4 blockade in preclinical tumor models.
Cancer Immunol Immunother
; 62(9): 1533-45, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23873089
9.
CTLA-4 blockade in tumor models: an overview of preclinical and translational research.
Cancer Immun
; 13: 5, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23390376
10.
Gene expression profiling of whole blood in ipilimumab-treated patients for identification of potential biomarkers of immune-related gastrointestinal adverse events.
J Transl Med
; 11: 75, 2013 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-23521917
11.
An immune-active tumor microenvironment favors clinical response to ipilimumab.
Cancer Immunol Immunother
; 61(7): 1019-31, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22146893
12.
An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation.
Oncoimmunology
; 11(1): 2030135, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35186440
13.
DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.
J Immunother Cancer
; 10(6)2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35688554
14.
Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors.
Cancer Discov
; 12(5): 1248-1265, 2022 05 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35176764
15.
Resistance to Durvalumab and Durvalumab plus Tremelimumab Is Associated with Functional STK11 Mutations in Patients with Non-Small Cell Lung Cancer and Is Reversed by STAT3 Knockdown.
Cancer Discov
; 11(11): 2828-2845, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34230008
16.
Cooperative Targeting of Immunotherapy-Resistant Melanoma and Lung Cancer by an AXL-Targeting Antibody-Drug Conjugate and Immune Checkpoint Blockade.
Cancer Res
; 81(7): 1775-1787, 2021 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33531370
17.
Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ.
Cancer Immunol Immunother
; 59(8): 1223-33, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20336294
18.
Identification and optimization of a novel series of [2.2.1]-oxabicyclo imide-based androgen receptor antagonists.
Bioorg Med Chem Lett
; 18(6): 1910-5, 2008 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18291644
19.
Cloning, expression and characterization of monkey (Macaca fascicularis) CD137.
Vet Immunol Immunopathol
; 126(3-4): 377-81, 2008 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18771806
20.
A structured light-based system for scanning subcutaneous tumors in laboratory animals.
Comp Med
; 58(3): 264-70, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18589868