Detalles de la búsqueda
1.
Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation.
J Enzyme Inhib Med Chem
; 38(1): 2209828, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37184096
2.
The Role of Genetics in the Development and Pharmacotherapy of Depression and Its Impact on Drug Discovery.
Int J Mol Sci
; 24(3)2023 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36769269
3.
In Silico Analysis, Anticonvulsant Activity, and Toxicity Evaluation of Schisandrin B in Zebrafish Larvae and Mice.
Int J Mol Sci
; 24(16)2023 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-37629132
4.
Synthesis, Structural and Behavioral Studies of Indole Derivatives D2AAK5, D2AAK6 and D2AAK7 as Serotonin 5-HT1A and 5-HT2A Receptor Ligands.
Molecules
; 28(1)2023 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36615578
5.
Development and Characterization of Novel Selective, Non-Basic Dopamine D2 Receptor Antagonists for the Treatment of Schizophrenia.
Molecules
; 28(10)2023 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37241951
6.
In vitro and in vivo evaluation of antioxidant and neuroprotective properties of antipsychotic D2AAK1.
Neurochem Res
; 47(6): 1778-1789, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35380398
7.
Allosteric Modulators of Dopamine D2 Receptors for Fine-Tuning of Dopaminergic Neurotransmission in CNS Diseases: Overview, Pharmacology, Structural Aspects and Synthesis.
Molecules
; 28(1)2022 Dec 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-36615372
8.
The Role of Lipids in Allosteric Modulation of Dopamine D2 Receptor-In Silico Study.
Molecules
; 27(4)2022 Feb 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-35209123
9.
Screening and Structure-Activity Relationship of D2AAK1 Derivatives for Potential Application in the Treatment of Neurodegenerative Diseases.
Molecules
; 27(7)2022 Mar 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-35408637
10.
Methods of Lysergic Acid Synthesis-The Key Ergot Alkaloid.
Molecules
; 27(21)2022 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36364148
11.
Experimental and Computational Structural Studies of 2,3,5-Trisubstituted and 1,2,3,5-Tetrasubstituted Indoles as Non-Competitive Antagonists of GluK1/GluK2 Receptors.
Molecules
; 27(8)2022 Apr 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35458681
12.
Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus.
Molecules
; 27(19)2022 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36235029
13.
Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands.
Arch Pharm (Weinheim)
; 354(5): e2000414, 2021 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-33543794
14.
Overcoming Depression with 5-HT2A Receptor Ligands.
Int J Mol Sci
; 23(1)2021 Dec 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35008436
15.
Docking-Based 3D-QSAR Studies for 1,3,4-oxadiazol-2-one Derivatives as FAAH Inhibitors.
Int J Mol Sci
; 22(11)2021 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34204026
16.
Some Dietary Phenolic Compounds Can Activate Thyroid Peroxidase and Inhibit Lipoxygenase-Preliminary Study in the Model Systems.
Int J Mol Sci
; 22(10)2021 May 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34065957
17.
1,2,4-Triazolin-5-thione derivatives with anticancer activity as CK1γ kinase inhibitors.
Bioorg Chem
; 99: 103806, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32279038
18.
Novel Positive Allosteric Modulators of µ Opioid Receptor-Insight from In Silico and In Vivo Studies.
Int J Mol Sci
; 21(22)2020 Nov 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33187107
19.
Preferential Coupling of Dopamine D2S and D2L Receptor Isoforms with Gi1 and Gi2 Proteins-In Silico Study.
Int J Mol Sci
; 21(2)2020 Jan 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31936673
20.
The Antipsychotic D2AAK1 as a Memory Enhancer for Treatment of Mental and Neurodegenerative Diseases.
Int J Mol Sci
; 21(22)2020 Nov 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-33238370