Detalles de la búsqueda
1.
Development and Validation of a Rapid LC-MS/MS Method for Quantifying Alvocidib: In Silico and In Vitro Metabolic Stability Estimation in Human Liver Microsomes.
Molecules
; 28(5)2023 Mar 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36903615
2.
Development of an LC-MS/MS Method for Quantification of Sapitinib in Human Liver Microsomes: In Silico and In Vitro Metabolic Stability Evaluation.
Molecules
; 28(5)2023 Mar 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36903565
3.
An Ultrafast UPLC-MS/MS Method for Characterizing the In Vitro Metabolic Stability of Acalabrutinib.
Molecules
; 28(20)2023 Oct 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-37894699
4.
Assessment of In Silico and In Vitro Selpercatinib Metabolic Stability in Human Liver Microsomes Using a Validated LC-MS/MS Method.
Molecules
; 28(6)2023 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36985590
5.
Investigation of Fenebrutinib Metabolism and Bioactivation Using MS3 Methodology in Ion Trap LC/MS.
Molecules
; 28(10)2023 May 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-37241965
6.
Molecular platforms based on biocompatible photoreactions for photomodulation of biological targets.
Org Biomol Chem
; 19(43): 9358-9368, 2021 11 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34632469
7.
Synthesis and Photophysical Properties of Fluorescein Esters as Potential Organic Semiconductor Materials.
J Fluoresc
; 31(5): 1489-1502, 2021 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-34287764
8.
A Validated LC-MS/MS Assay for the Simultaneous Quantification of the FDA-Approved Anticancer Mixture (Encorafenib and Binimetinib): Metabolic Stability Estimation.
Molecules
; 26(9)2021 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34063139
9.
EGFR Inhibitor Gefitinib Induces Cardiotoxicity through the Modulation of Cardiac PTEN/Akt/FoxO3a Pathway and Reactive Metabolites Formation: In Vivo and in Vitro Rat Studies.
Chem Res Toxicol
; 33(7): 1719-1728, 2020 07 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32370496
10.
Detection and characterization of olmutinib reactive metabolites by LC-MS/MS: Elucidation of bioactivation pathways.
J Sep Sci
; 43(4): 708-718, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31788977
11.
Galeon: A Biologically Active Molecule with In Silico Metabolite Prediction, In Vitro Metabolic Profiling in Rat Liver Microsomes, and In Silico Binding Mechanisms with CYP450 Isoforms.
Molecules
; 25(24)2020 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-33322201
12.
Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation.
Molecules
; 25(21)2020 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-33126762
13.
A reliable and stable method for the determination of foretinib in human plasma by LC-MS/MS: Application to metabolic stability investigation and excretion rate.
Eur J Mass Spectrom (Chichester)
; 24(4): 344-351, 2018 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-29629565
14.
Enzyme-instructed self-assembly with photo-responses for the photo-regulation of cancer cells.
Org Biomol Chem
; 15(33): 6892-6895, 2017 Aug 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-28766648
15.
A photo-degradable supramolecular hydrogel for selective delivery of microRNA into 3D-cultured cells.
Org Biomol Chem
; 15(10): 2191-2198, 2017 Mar 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28220178
16.
An LC-MS/MS method for rapid and sensitive high-throughput simultaneous determination of various protein kinase inhibitors in human plasma.
Biomed Chromatogr
; 31(2)2017 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-27450926
17.
Development and validation of HPLC-MS/MS method for the determination of lixivaptan in mouse plasma and its application in a pharmacokinetic study.
Biomed Chromatogr
; 31(11)2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28493402
18.
Biophysical and In Silico Studies of the Interaction between the Anti-Viral Agents Acyclovir and Penciclovir, and Human Serum Albumin.
Molecules
; 22(11)2017 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29113080
19.
Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure-activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor.
Bioorg Med Chem
; 24(8): 1898-908, 2016 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26988802
20.
A highly efficient and sensitive LC-MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability study.
Biomed Chromatogr
; 30(8): 1248-55, 2016 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26683307