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1.
Development of Novel Methods for QSAR Modeling by Machine Learning Repeatedly: A Case Study on Drug Distribution to Each Tissue.
J Chem Inf Model
; 64(9): 3662-3669, 2024 May 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38639496
2.
Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption.
Drug Metab Dispos
; 51(3): 318-328, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36810197
3.
Prediction of Compound Plasma Concentration-Time Profiles in Mice Using Random Forest.
Mol Pharm
; 20(6): 3060-3072, 2023 06 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37096989
4.
Stabilization and quantitative measurement of nicotinamide adenine dinucleotide in human whole blood using dried blood spot sampling.
Anal Bioanal Chem
; 415(5): 775-785, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36504284
5.
Development of a Novel In Silico Classification Model to Assess Reactive Metabolite Formation in the Cysteine Trapping Assay and Investigation of Important Substructures.
Biomolecules
; 14(5)2024 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38785942
6.
Development of a 2D-QSAR Model for Tissue-to-Plasma Partition Coefficient Value with High Accuracy Using Machine Learning Method, Minimum Required Experimental Values, and Physicochemical Descriptors.
Eur J Drug Metab Pharmacokinet
; 48(4): 341-352, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-37266860
7.
On the difficulty of validating molecular generative models realistically: a case study on public and proprietary data.
J Cheminform
; 15(1): 112, 2023 Nov 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-37990215
8.
Cerebral and extracerebral distribution of radioactivity associated with oxytocin in rabbits after intranasal administration: Comparison of TTA-121, a newly developed oxytocin formulation, with Syntocinon.
PLoS One
; 16(12): e0261451, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34929003
9.
Hepatic and intestinal contributions to pharmacokinetic interaction of indinavir with amprenavir, nelfinavir and saquinavir in rats.
Antivir Chem Chemother
; 13(1): 17-26, 2002 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-12180646
10.
Relationship between excretion clearance of rhodamine 123 and P-glycoprotein (Pgp) expression induced by representative Pgp inducers.
Biol Pharm Bull
; 29(4): 779-84, 2006 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-16595917
11.
In vivo effects of cyclosporin A and ketoconazole on the pharmacokinetics of representative substrates for P-glycoprotein and cytochrome P450 (CYP) 3A in rats.
Biol Pharm Bull
; 28(2): 316-22, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15684491
12.
Effect of chronic administration of ritonavir on function of cytochrome P450 3A and P-glycoprotein in rats.
Biol Pharm Bull
; 28(1): 130-7, 2005 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-15635177
13.
Sensitive and simultaneous determination of HIV protease inhibitors in rat biological samples by liquid chromatography-mass spectrometry.
Biomed Chromatogr
; 16(4): 267-73, 2002 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-11933027
14.
Evaluation of factors to decrease plasma concentration of an HIV protease inhibitor, saquinavir in ethanol-treated rats.
Biol Pharm Bull
; 27(2): 203-9, 2004 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-14758034
15.
Pharmacokinetic characterization of a human immunodeficiency virus protease inhibitor, saquinavir, during ethanol intake in rats.
Biopharm Drug Dispos
; 24(8): 335-44, 2003 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-14595702
16.
Effect of indinavir on the intestinal exsorption of amprenavir, saquinavir and nelfinavir after intravenous administration in rats.
Biol Pharm Bull
; 26(2): 199-204, 2003 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-12576680
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