Detalles de la búsqueda
1.
JNJ-73763989 and bersacapavir treatment in nucleos(t)ide analog suppressed patients with chronic hepatitis B: REEF-2.
J Hepatol
; 2024 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38583491
2.
Safety, antiviral activity and pharmacokinetics of JNJ-64530440, a novel capsid assembly modulator, as 4 week monotherapy in treatment-naive patients with chronic hepatitis B virus infection.
J Antimicrob Chemother
; 77(4): 1102-1110, 2022 03 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-35040959
3.
Antiviral Activity, Safety, and Pharmacokinetics of Capsid Assembly Modulator NVR 3-778 in Patients with Chronic HBV Infection.
Gastroenterology
; 156(5): 1392-1403.e7, 2019 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-30625297
4.
Antiviral Activity, Safety, and Pharmacokinetics of AL-794, a Novel Oral Influenza Endonuclease Inhibitor: Results of an Influenza Human Challenge Study.
J Infect Dis
; 219(2): 177-185, 2019 01 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30053042
5.
Short-Duration AL-335, Odalasvir, With or Without Simeprevir, in Patients With HCV GT1 or 3 Infection Without Cirrhosis.
Hepatology
; 68(6): 2145-2157, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30070722
6.
Single- and multiple-dose pharmacokinetics and safety of pimodivir, a novel, non-nucleoside polymerase basic protein 2 subunit inhibitor of the influenza A virus polymerase complex, and interaction with oseltamivir: a Phase 1 open-label study in healthy volunteers.
Br J Clin Pharmacol
; 84(11): 2663-2672, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30098042
7.
Efficacy, safety and pharmacokinetics of simeprevir and TMC647055/ritonavir with or without ribavirin and JNJ-56914845 in HCV genotype 1 infection.
BMC Gastroenterol
; 17(1): 26, 2017 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28187751
8.
Pharmacokinetic evaluation of the interaction between etravirine and rifabutin or clarithromycin in HIV-negative, healthy volunteers: results from two Phase 1 studies.
J Antimicrob Chemother
; 69(3): 728-34, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24155058
9.
Pharmacokinetics and pharmacodynamics of boosted once-daily darunavir.
J Antimicrob Chemother
; 69(10): 2591-605, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24951533
10.
Bioavailability and bioequivalence of a darunavir 800-mg tablet formulation compared with the 400-mg tablet formulation.
Int J Clin Pharmacol Ther
; 52(9): 805-16, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25109510
11.
Cobicistat-boosted darunavir in HIV-1-infected adults: week 48 results of a Phase IIIb, open-label single-arm trial.
AIDS Res Ther
; 11: 39, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25926858
12.
Single-dose pharmacokinetics of pediatric and adult formulations of etravirine and swallowability of the 200-mg tablet: results from three Phase 1 studies.
Int J Clin Pharmacol Ther
; 51(9): 725-37, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23924679
13.
Pharmacokinetics, Safety, and Tolerability of the siRNA JNJ-73763989 in Healthy Chinese Adult Participants.
Clin Pharmacol Drug Dev
; 12(2): 175-180, 2023 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36415122
14.
Pharmacokinetics of JNJ-73763989 and JNJ-56136379 (Bersacapavir) in Participants With Moderate Hepatic Impairment.
J Clin Pharmacol
; 63(6): 732-741, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36786053
15.
Efficacy and safety of the siRNA JNJ-73763989 and the capsid assembly modulator JNJ-56136379 (bersacapavir) with nucleos(t)ide analogues for the treatment of chronic hepatitis B virus infection (REEF-1): a multicentre, double-blind, active-controlled, randomised, phase 2b trial.
Lancet Gastroenterol Hepatol
; 8(9): 790-802, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37442152
16.
Drug-Drug Interactions With the Hepatitis B Virus Capsid Assembly Modulator JNJ-56136379 (Bersacapavir).
Clin Pharmacol Drug Dev
; 11(12): 1419-1429, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36062869
17.
JNJ-73763989 pharmacokinetics and safety: Liver-targeted siRNAs against hepatitis B virus, in Japanese and non-Japanese healthy adults, and combined with JNJ-56136379 and a nucleos(t)ide analogue in patients with chronic hepatitis B.
Antivir Ther
; 27(3): 13596535221093856, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35695169
18.
Pharmacokinetic interactions of maraviroc with darunavir-ritonavir, etravirine, and etravirine-darunavir-ritonavir in healthy volunteers: results of two drug interaction trials.
Antimicrob Agents Chemother
; 55(5): 2290-6, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21383098
19.
Pharmacokinetics, safety and tolerability of single- and multiple-ascending doses of JNJ-64530440, a novel hepatitis B virus capsid assembly modulator, in healthy volunteers.
Antivir Ther
; 26(1-2): 13-24, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-35485346
20.
Minimal pharmacokinetic interaction between the human immunodeficiency virus nonnucleoside reverse transcriptase inhibitor etravirine and the integrase inhibitor raltegravir in healthy subjects.
Antimicrob Agents Chemother
; 52(12): 4228-32, 2008 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18838586