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1.
Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund's adjuvant-induced paw inflammation model.
Inflamm Res
; 72(8): 1649-1664, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37498393
2.
Bony Fish Arachidonic Acid 15-Lipoxygenases Exhibit Different Catalytic Properties than Their Mammalian Orthologs, Suggesting Functional Enzyme Evolution during Vertebrate Development.
Int J Mol Sci
; 24(18)2023 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37762455
3.
Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities.
Int J Mol Sci
; 24(12)2023 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37373195
4.
Functional Characterization of Transgenic Mice Overexpressing Human 15-Lipoxygenase-1 (ALOX15) under the Control of the aP2 Promoter.
Int J Mol Sci
; 24(5)2023 Mar 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36902243
5.
The Reaction Specificity of Mammalian ALOX15 Orthologs is Changed During Late Primate Evolution and These Alterations Might Offer Evolutionary Advantages for Hominidae.
Front Cell Dev Biol
; 10: 871585, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35531094
6.
Male Knock-in Mice Expressing an Arachidonic Acid Lipoxygenase 15B (Alox15B) with Humanized Reaction Specificity Are Prematurely Growth Arrested When Aging.
Biomedicines
; 10(6)2022 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35740398
7.
N-Substituted 5-(1H-Indol-2-yl)-2-methoxyanilines Are Allosteric Inhibitors of the Linoleate Oxygenase Activity of Selected Mammalian ALOX15 Orthologs: Mechanism of Action.
J Med Chem
; 65(3): 1979-1995, 2022 02 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35073698
8.
Oxygenation of endocannabinoids by mammalian lipoxygenase isoforms.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1866(6): 158918, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33662546
9.
Understanding the Dual Inhibition of COX-2 and Carbonic Anhydrase-II by Celecoxib and CG100649 Using Density Functional Theory Calculations and other Molecular Modelling Approaches.
Protein Pept Lett
; 22(10): 903-12, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26095375
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