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1.
The unintended mitochondrial uncoupling effects of the FDA-approved anti-helminth drug nitazoxanide mitigates experimental parkinsonism in mice.
J Biol Chem
; 292(38): 15731-15743, 2017 09 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-28798236
2.
Correction: The unintended mitochondrial uncoupling effects of the FDA-approved anti-helminth drug nitazoxanide mitigates experimental parkinsonism in mice.
J Biol Chem
; 297(1): 100864, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-34144437
3.
Regulation of PSMB5 protein and ß subunits of mammalian proteasome by constitutively activated signal transducer and activator of transcription 3 (STAT3): potential role in bortezomib-mediated anticancer therapy.
J Biol Chem
; 289(18): 12612-22, 2014 May 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-24627483
4.
Fructose induces mitochondrial dysfunction and triggers apoptosis in skeletal muscle cells by provoking oxidative stress.
Apoptosis
; 20(7): 930-47, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25913123
5.
Synthesis and Biological evaluation of novel 4ß-[(5-substituted)-1,2,3,4-tetrazolyl] podophyllotoxins as anticancer compounds.
Bioorg Med Chem Lett
; 25(14): 2860-3, 2015 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26022842
6.
Thee-component, one-pot synthesis of hexahydroazepino[3,4-b]indole and tetrahydro-1H-pyrido[3,4-b]indole derivatives and evaluation of their cytotoxicity.
Bioorg Med Chem Lett
; 24(18): 4501-4503, 2014 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25176193
7.
The USP10/13 inhibitor, spautin-1, attenuates the progression of glioblastoma by independently regulating RAF-ERK mediated glycolysis and SKP2.
Biochim Biophys Acta Mol Basis Dis
; 1870(7): 167291, 2024 Jun 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38857836
8.
Anti-cancer evaluation of carboxamides of furano-sesquiterpene carboxylic acids from the soft coral Sinularia kavarattiensis.
Bioorg Med Chem Lett
; 23(23): 6234-8, 2013 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24144848
9.
The mitochondrial uncoupling effects of nitazoxanide enhances cellular autophagy and promotes the clearance of α-synuclein: Potential role of AMPK-JNK pathway.
Cell Signal
; 109: 110769, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37315747
10.
Identification of RBMX as a splicing regulator in Parkinsonian mimetic induced alternative splicing of α-synuclein.
Biochim Biophys Acta Gene Regul Mech
; 1865(4): 194825, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35577270
11.
Stereoselective total synthesis of (+)-oploxyne A, (-)-oploxyne B, and their C-10 epimers and structure revision of natural oploxyne B.
J Org Chem
; 76(8): 2568-76, 2011 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21413759
12.
Synthesis of a new 4-aza-2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents.
Bioorg Med Chem
; 19(7): 2349-58, 2011 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21402478
13.
Extracellular-Signal-Regulated Kinase Inhibition Switches APP Processing from ß- to α-Secretase under Oxidative Stress: Modulation of ADAM10 by SIRT1/NF-κB Signaling.
ACS Chem Neurosci
; 12(21): 4175-4186, 2021 11 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34647720
14.
Selective cancer targeting via aberrant behavior of cancer cell-associated glucocorticoid receptor.
Mol Ther
; 17(4): 623-31, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19223869
15.
Embelin averts MPTP-induced dysfunction in mitochondrial bioenergetics and biogenesis via activation of SIRT1.
Biochim Biophys Acta Bioenerg
; 1861(3): 148157, 2020 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31987812
16.
The mitochondrial effects of embelin are independent of its MAP kinase regulation: Role of p53 in conferring selectivity towards cancer cells.
Mitochondrion
; 46: 158-163, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29715507
17.
The deglycase activity of DJ-1 mitigates α-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson's disease.
Free Radic Biol Med
; 135: 28-37, 2019 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30796974
18.
Identification of an Alternatively Spliced α-Synuclein Isoform That Generates a 41-Amino Acid N-Terminal Truncated Peptide, 41-syn: Role in Dopamine Homeostasis.
ACS Chem Neurosci
; 9(12): 2948-2958, 2018 12 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-29996045
19.
Oxidative stress-induced iron signaling is responsible for peroxide-dependent oxidation of dichlorodihydrofluorescein in endothelial cells: role of transferrin receptor-dependent iron uptake in apoptosis.
Circ Res
; 92(1): 56-63, 2003 Jan 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-12522121
20.
Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium.
Biochem J
; 389(Pt 2): 527-39, 2005 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15799720