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1.
Exploration of oxadiazole clubbed benzhydrylpiperazine pharmacophoric features as structural feature for antidepressant activity: In vitro, in vivo and in silico analysis.
Bioorg Chem
; 144: 107148, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38306828
2.
Identification of potential inhibitors of Zika virus targeting NS3 helicase using molecular dynamics simulations and DFT studies.
Mol Divers
; 27(4): 1689-1701, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-36063275
3.
Design, synthesis, biological evaluation of 3,5-diaryl-4,5-dihydro-1H-pyrazole carbaldehydes as non-purine xanthine oxidase inhibitors: Tracing the anticancer mechanism via xanthine oxidase inhibition.
Bioorg Chem
; 107: 104620, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33454509
4.
Investigation of indole functionalized pyrazoles and oxadiazoles as anti-inflammatory agents: Synthesis, in-vivo, in-vitro and in-silico analysis.
Bioorg Chem
; 114: 105068, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34130110
5.
A perspective on potential target proteins of COVID-19: Comparison with SARS-CoV for designing new small molecules.
Bioorg Chem
; 104: 104326, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33142431
6.
E-pharmacophore guided discovery of pyrazolo[1,5-c]quinazolines as dual inhibitors of topoisomerase-I and histone deacetylase.
Bioorg Chem
; 94: 103409, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31732194
7.
Exploration of Pd-catalysed four-component tandem reaction for one-pot assembly of pyrazolo[1,5-c]quinazolines as potential EGFR inhibitors.
Bioorg Chem
; 93: 103314, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31590041
8.
Toward an Understanding of Structural Insights of Xanthine and Aldehyde Oxidases: An Overview of their Inhibitors and Role in Various Diseases.
Med Res Rev
; 38(4): 1073-1125, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28672082
9.
Association of CYP2C19*2 and ALDH1A1*1/*2 variants with disease outcome in breast cancer patients: results of a global screening array.
Eur J Clin Pharmacol
; 74(10): 1291-1298, 2018 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-29938344
10.
Anticancer activity of dihydropyrazolo[1,5-c]quinazolines against rat C6 glioma cells via inhibition of topoisomerase II.
Arch Pharm (Weinheim)
; 351(6): e1800023, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29737542
11.
Mechanism-based inactivation of cytochromes by furan epoxide: unraveling the molecular mechanism.
Inorg Chem
; 52(23): 13496-508, 2013 Dec 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-24236636
12.
Flavonoids as P-glycoprotein inhibitors for multidrug resistance in cancer: an in-silico approach.
J Biomol Struct Dyn
; 41(16): 7627-7639, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36120941
13.
Molecular Docking and In Vitro Anticancer Screening of Synthesized Arylthiazole linked 2H-indol-2-one Derivatives as VEGFR-2 Kinase Inhibitors.
Anticancer Agents Med Chem
; 22(11): 2166-2180, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-34792005
14.
Computational investigation of potential inhibitors of novel coronavirus 2019 through structure-based virtual screening, molecular dynamics and density functional theory studies.
J Biomol Struct Dyn
; 39(12): 4449-4461, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32666910
15.
Rationalization of the activity Profile of Pyruvate Kinase Isozyme M2 (PKM2) Inhibitors using 3D QSAR.
Curr Top Med Chem
; 21(25): 2258-2271, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34348626
16.
Is highly expressed ACE 2 in pregnant women "a curse" in times of COVID-19 pandemic?
Life Sci
; 264: 118676, 2021 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33129880
17.
Medicinal Perspective of Indole Derivatives: Recent Developments and Structure-Activity Relationship Studies.
Curr Drug Targets
; 21(9): 864-891, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32156235
18.
Anticancer potential of some imidazole and fused imidazole derivatives: exploring the mechanism via epidermal growth factor receptor (EGFR) inhibition.
RSC Med Chem
; 11(8): 923-939, 2020 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33479688
19.
Nanotechnology for COVID-19: Therapeutics and Vaccine Research.
ACS Nano
; 14(7): 7760-7782, 2020 07 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32571007
20.
A Review on Quinoline Derived Scaffolds as Anti-HIV Agents.
Mini Rev Med Chem
; 19(6): 510-526, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30338737