Detalles de la búsqueda
1.
Mass spectrometry-based methods to characterize highly heterogeneous biopharmaceuticals, vaccines, and nonbiological complex drugs at the intact-mass level.
Mass Spectrom Rev
; 43(1): 139-165, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-36582075
2.
Probing the Architecture of Multisubunit Protein Complexes with In-line Disulfide Reduction and Native MS Analysis.
Anal Chem
; 96(21): 8243-8248, 2024 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38733603
3.
Structural Characterization of a Pathogenic Antibody Underlying Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT).
Anal Chem
; 96(16): 6209-6217, 2024 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38607319
4.
Characterization of Large Immune Complexes with Size Exclusion Chromatography and Native Mass Spectrometry Supplemented with Gas Phase Ion Chemistry.
Anal Chem
; 2024 Feb 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38319243
5.
Reverse Engineering of a Pathogenic Antibody Reveals the Molecular Mechanism of Vaccine-Induced Immune Thrombotic Thrombocytopenia.
J Am Chem Soc
; 145(46): 25203-25213, 2023 11 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-37949820
6.
Rapid Evaluation of the Extent of Haptoglobin Glycosylation Using Orthogonal Intact-Mass MS Approaches and Multivariate Analysis.
Anal Chem
; 94(12): 5140-5148, 2022 03 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-35285615
7.
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.
Nat Methods
; 16(7): 595-602, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31249422
8.
Charge Manipulation Using Solution and Gas-Phase Chemistry to Facilitate Analysis of Highly Heterogeneous Protein Complexes in Native Mass Spectrometry.
Anal Chem
; 93(7): 3337-3342, 2021 02 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-33566581
9.
The challenge of structural heterogeneity in the native mass spectrometry studies of the SARS-CoV-2 spike protein interactions with its host cell-surface receptor.
Anal Bioanal Chem
; 413(29): 7205-7214, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34389878
10.
Towards better understanding of the heparin role in NETosis: feasibility of using native mass spectrometry to monitor interactions of neutrophil elastase with heparin oligomers.
Int J Mass Spectrom
; 4632021 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-33692650
11.
Platelet Factor 4 Interactions with Short Heparin Oligomers: Implications for Folding and Assembly.
Biophys J
; 119(7): 1371-1379, 2020 10 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32348723
12.
The Utility of Native MS for Understanding the Mechanism of Action of Repurposed Therapeutics in COVID-19: Heparin as a Disruptor of the SARS-CoV-2 Interaction with Its Host Cell Receptor.
Anal Chem
; 92(16): 10930-10934, 2020 08 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-32678978
13.
Identification of Protein Recognition Elements within Heparin Chains Using Enzymatic Foot-Printing in Solution and Online SEC/MS.
Anal Chem
; 92(11): 7565-7573, 2020 06 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32347711
14.
Evaluation of top-down mass spectrometry and ion-mobility spectroscopy as a means of mapping protein-binding motifs within heparin chains.
Analyst
; 145(8): 3090-3099, 2020 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32150181
15.
Co(II) and Ni(II) binding of the Escherichia coli transcriptional repressor RcnR orders its N terminus, alters helix dynamics, and reduces DNA affinity.
J Biol Chem
; 293(1): 324-332, 2018 01 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29150441
16.
Exploiting His-Tags for Absolute Quantitation of Exogenous Recombinant Proteins in Biological Matrices: Ruthenium as a Protein Tracer.
Anal Chem
; 91(11): 7189-7198, 2019 06 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31083917
17.
LC/MS at the whole protein level: Studies of biomolecular structure and interactions using native LC/MS and cross-path reactive chromatography (XP-RC) MS.
Methods
; 144: 14-26, 2018 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29702225
18.
Mass Spectrometry Reveals a Multifaceted Role of Glycosaminoglycan Chains in Factor Xa Inactivation by Antithrombin.
Biochemistry
; 57(32): 4880-4890, 2018 08 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-29999301
19.
Integration of On-Column Chemical Reactions in Protein Characterization by Liquid Chromatography/Mass Spectrometry: Cross-Path Reactive Chromatography.
Anal Chem
; 90(2): 1348-1355, 2018 01 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-29240412
20.
Multi-step conformational transitions in heat-treated protein therapeutics can be monitored in real time with temperature-controlled electrospray ionization mass spectrometry.
Analyst
; 143(3): 670-677, 2018 Feb 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29303166