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1.
Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex.
Mol Cell
; 53(4): 534-48, 2014 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-24486017
2.
Design and synthesis of benzopyran-based inhibitors of the hypoxia-inducible factor-1 pathway with improved water solubility.
J Enzyme Inhib Med Chem
; 32(1): 992-1001, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28766956
3.
Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors.
Bioorg Med Chem Lett
; 21(18): 5528-32, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21831638
4.
Targeting HIF-activated collagen prolyl 4-hydroxylase expression disrupts collagen deposition and blocks primary and metastatic uveal melanoma growth.
Oncogene
; 40(33): 5182-5191, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34218269
5.
Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show?
Biochim Biophys Acta
; 1795(2): 162-72, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19344680
6.
EZH2 targeting reduces medulloblastoma growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathway.
Oncogene
; 39(5): 1041-1048, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31582835
7.
Correction: EZH2 targeting reduces medulloblastoma growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathway.
Oncogene
; 39(5): 1165, 2020 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-31676871
8.
Proteasomal inhibition attenuates transcriptional activity of hypoxia-inducible factor 1 (HIF-1) via specific effect on the HIF-1alpha C-terminal activation domain.
Mol Cell Biol
; 26(15): 5895-907, 2006 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16847340
9.
Arylsulfonamide 64B Inhibits Hypoxia/HIF-Induced Expression of c-Met and CXCR4 and Reduces Primary Tumor Growth and Metastasis of Uveal Melanoma.
Clin Cancer Res
; 25(7): 2206-2218, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30563937
10.
Does inhibition of degradation of hypoxia-inducible factor (HIF) alpha always lead to activation of HIF? Lessons learnt from the effect of proteasomal inhibition on HIF activity.
J Cell Biochem
; 104(2): 536-44, 2008 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18059036
11.
Rational design of minimal hypoxia-inducible enhancers.
Biochem Biophys Res Commun
; 370(4): 613-8, 2008 Jun 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-18402769
12.
Regulation of gene expression by hypoxia: integration of the HIF-transduced hypoxic signal at the hypoxia-responsive element.
Clin Chim Acta
; 395(1-2): 6-13, 2008 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-18505681
13.
DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX.
Mol Cell Biol
; 24(13): 5757-66, 2004 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15199132
14.
Purifying Properly Folded Cysteine-rich, Zinc Finger Containing Recombinant Proteins for Structural Drug Targeting Studies: the CH1 Domain of p300 as a Case Example.
Bio Protoc
; 7(17)2017 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28966947
15.
A novel small-molecule arylsulfonamide causes energetic stress and suppresses breast and lung tumor growth and metastasis.
Oncotarget
; 8(59): 99245-99260, 2017 Nov 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-29245898
16.
Expression of the hypoxia marker carbonic anhydrase IX is critically dependent on SP1 activity. Identification of a novel type of hypoxia-responsive enhancer.
Cancer Res
; 63(5): 917-22, 2003 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12615703
17.
Lowered oxygen tension induces expression of the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1 alpha stabilization: a role for phosphatidylinositol 3'-kinase.
Cancer Res
; 62(15): 4469-77, 2002 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12154057
18.
A role for activated Cdc42 in glioblastoma multiforme invasion.
Oncotarget
; 7(35): 56958-56975, 2016 08 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27486972
19.
Comment on the role of FIH in the inhibitory effect of bortezomib on hypoxia-inducible factor-1.
Blood
; 111(10): 5258-9; author reply 5259-61, 2008 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18467614
20.
Taking a HIF pill for old age diseases?
Aging (Albany NY)
; 10(3): 290-292, 2018 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29500331