Detalles de la búsqueda
1.
Characterization of cardiovascular profile of anti-influenza drug peramivir: A reverse-translational study using the isoflurane-anesthetized dog.
J Pharmacol Sci
; 154(3): 218-224, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38395523
2.
Analyses of the onset mechanisms of cardio-stimulatory action by aciclovir.
J Pharmacol Sci
; 154(4): 294-300, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38485347
3.
Characterization of electropharmacological profile of an anti-atrial fibrillatory drug vernakalant along with potential risk toward torsade de pointes: Translational studies using isoflurane-anesthetized dogs and isolated rat aortic preparations.
J Pharmacol Sci
; 152(4): 201-209, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37344055
4.
Peripheral Regulation of Central Brain-Derived Neurotrophic Factor Expression through the Vagus Nerve.
Int J Mol Sci
; 24(4)2023 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36834953
5.
Role of cardiac α1-adrenoreceptors for the torsadogenic action of IKr blocker nifekalant in the anesthetized atrioventricular block rabbit.
J Pharmacol Sci
; 150(2): 67-73, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-36055753
6.
Roles of IK,ACh for perpetuating atrial fibrillation: Effects of atrial-selective K+ channel inhibitor AVE0118 and class I drugs on the persistent atrial fibrillation canine model.
J Pharmacol Sci
; 149(4): 175-178, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-35717070
7.
Analysis of clinically-reported, memantine-induced cardiovascular adverse responses using the halothane-anesthetized dogs: Reverse translational study.
J Pharmacol Sci
; 148(4): 343-350, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35300808
8.
Imatinib induces diastolic dysfunction and ventricular early-repolarization delay in the halothane-anesthetized dogs: Class effects of tyrosine kinase inhibitors.
J Pharmacol Sci
; 150(3): 154-162, 2022 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-36184120
9.
Appraisal of ICH E14/S7B Q&As adopted in February 2022 using thorough QT/QTc study data for α4-integrin antagonist carotegrast methyl in Japanese healthy subjects.
J Pharmacol Sci
; 150(3): 191-199, 2022 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-36184124
10.
Simultaneous analyses of hemodynamic and electrophysiological effects of oseltamivir along with its pharmacokinetic profile using the canine paroxysmal atrial fibrillation model.
J Pharmacol Sci
; 148(1): 179-186, 2022 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-34924124
11.
Impact of head-up tilt on expiratory negative airway pressure ventilation-induced cardiovascular hemodynamics in the halothane-anesthetized intact microminipigs.
Heart Vessels
; 37(10): 1808-1815, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-35426504
12.
Effects of Cardiac Massage and ß-Blocker Pretreatment on the Success Rate of Cardiopulmonary Resuscitation Assessed by the Canine Ischemia/Reperfusion-Induced Ventricular Fibrillation Model.
Circ J
; 85(10): 1885-1891, 2021 09 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-33762525
13.
In vivo comparison of dl-sotalol-induced electrocardiographic responses among halothane anesthesia, isoflurane anesthesia with nitrous oxide, and conscious state.
J Pharmacol Sci
; 145(1): 16-22, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-33357775
14.
In vivo analysis of concentration-dependent effects of halothane or isoflurane inhalation on the electrocardiographic and hemodynamic variables in dogs.
J Pharmacol Sci
; 145(3): 268-272, 2021 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-33602507
15.
Reverse translational analysis of clinically reported, lamotrigine-induced cardiovascular adverse events using the halothane-anesthetized dogs.
Heart Vessels
; 36(3): 424-429, 2021 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-33136260
16.
In vivo characterization of anti-atrial fibrillatory potential and pharmacological safety profile of INa,L plus IKr inhibitor ranolazine using the halothane-anesthetized dogs.
Heart Vessels
; 36(7): 1088-1097, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-33763729
17.
Utilization of the chronic atrioventricular block cynomolgus monkey as an in vivo model to evaluate drug interaction-associated torsade de pointes.
J Pharmacol Sci
; 142(4): 172-175, 2020 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-31982331
18.
Characterization of microminipig as a laboratory animal for pharmacological study by analyzing bepridil-induced cardiovascular responses.
J Pharmacol Sci
; 143(1): 56-59, 2020 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-32144028
19.
Risperidone alone did not induce torsade de pointes: Experimental evidence from the chronic atrioventricular block model dogs.
J Pharmacol Sci
; 143(4): 330-332, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32499094
20.
In vivo analysis of the effects of intravenously as well as orally administered moxifloxacin on the pharmacokinetic and electrocardiographic variables along with its torsadogenic action in the chronic atrioventricular block cynomolgus monkeys.
J Pharmacol Sci
; 143(4): 272-280, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32499095