Detalles de la búsqueda
1.
A PEGylated liposomal formulation of prochlorperazine that limits brain exposure but retains dynamin II activity: A potential adjuvant therapy for cancer patients receiving chemotherapeutic mAbs.
Nanomedicine
; 56: 102733, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38199450
2.
Dose-Dependent Production of Anti-PEG IgM after Intramuscular PEGylated-Hydrogenated Soy Phosphatidylcholine Liposomes, but Not Lipid Nanoparticle Formulations of DNA, Correlates with the Plasma Clearance of PEGylated Liposomal Doxorubicin in Rats.
Mol Pharm
; 20(7): 3494-3504, 2023 07 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-37256791
3.
Dose-Dependent Effect of Phenothiazines as Dynamin II Inhibitors on the Uptake of PEGylated Liposomes by Endocytic Cells and In Vivo Pharmacokinetics of PEGylated Liposomal Doxorubicin in Rats.
Mol Pharm
; 20(9): 4468-4477, 2023 09 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37548597
4.
Trisulfide-Bearing PEG Brush Polymers Donate Hydrogen Sulfide and Ameliorate Cellular Oxidative Stress.
Biomacromolecules
; 21(12): 5292-5305, 2020 12 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33210534
5.
Cetuximab Exhibits Sex Differences in Lymphatic Exposure after Intravenous Administration in Rats in the Absence of Differences in Plasma Exposure.
Pharm Res
; 37(11): 224, 2020 Oct 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-33078255
6.
The impact of size and charge on the pulmonary pharmacokinetics and immunological response of the lungs to PLGA nanoparticles after intratracheal administration to rats.
Nanomedicine
; 30: 102291, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32841737
7.
Aerosol Pirfenidone Pharmacokinetics after Inhaled Delivery in Sheep: a Viable Approach to Treating Idiopathic Pulmonary Fibrosis.
Pharm Res
; 37(1): 3, 2019 Dec 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31823096
8.
Microfluidic preparation of drug-loaded PEGylated liposomes, and the impact of liposome size on tumour retention and penetration.
J Liposome Res
; 29(1): 1-9, 2019 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-29020849
9.
Subunit-based mucosal vaccine delivery systems for pulmonary delivery - Are they feasible?
Drug Dev Ind Pharm
; 45(6): 882-894, 2019 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-30767591
10.
Reducing Dendrimer Generation and PEG Chain Length Increases Drug Release and Promotes Anticancer Activity of PEGylated Polylysine Dendrimers Conjugated with Doxorubicin via a Cathepsin-Cleavable Peptide Linker.
Mol Pharm
; 15(10): 4568-4576, 2018 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30107748
11.
An Evaluation of Optimal PEGylation Strategies for Maximizing the Lymphatic Exposure and Antiviral Activity of Interferon after Subcutaneous Administration.
Biomacromolecules
; 18(9): 2866-2875, 2017 Sep 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28731677
12.
Influence of Size and Shape on the Biodistribution of Nanoparticles Prepared by Polymerization-Induced Self-Assembly.
Biomacromolecules
; 18(12): 3963-3970, 2017 Dec 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28880542
13.
Lymphatic transport and lymph node targeting of methotrexate-conjugated PEGylated dendrimers are enhanced by reducing the length of the drug linker or masking interactions with the injection site.
Nanomedicine
; 13(8): 2485-2494, 2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28821463
14.
Hyaluronic Acid Molecular Weight Determines Lung Clearance and Biodistribution after Instillation.
Mol Pharm
; 13(6): 1904-14, 2016 06 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27157508
15.
Conjugation of 10 kDa Linear PEG onto Trastuzumab Fab' Is Sufficient to Significantly Enhance Lymphatic Exposure while Preserving in Vitro Biological Activity.
Mol Pharm
; 13(4): 1229-41, 2016 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-26871003
16.
A Comparison of the Pharmacokinetics and Pulmonary Lymphatic Exposure of a Generation 4 PEGylated Dendrimer Following Intravenous and Aerosol Administration to Rats and Sheep.
Pharm Res
; 33(2): 510-25, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26486513
17.
Disposition and safety of inhaled biodegradable nanomedicines: Opportunities and challenges.
Nanomedicine
; 12(6): 1703-24, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27033834
18.
PEGylation does not significantly change the initial intravenous or subcutaneous pharmacokinetics or lymphatic exposure of trastuzumab in rats but increases plasma clearance after subcutaneous administration.
Mol Pharm
; 12(3): 794-809, 2015 Mar 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-25644368
19.
Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous administration in rats.
Mol Pharm
; 12(2): 432-43, 2015 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-25485615
20.
Molecular weight (hydrodynamic volume) dictates the systemic pharmacokinetics and tumour disposition of PolyPEG star polymers.
Nanomedicine
; 11(8): 2099-108, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26343493