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1.
A simple and rapid pre-clinical in vivo model reveals comparative cardiotoxicity profiles of kinase inhibitors.
Toxicol Appl Pharmacol
; 486: 116944, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38677603
2.
Applications of promiscuity of FDA-approved kinase inhibitors in drug repositioning and toxicity.
Toxicol Appl Pharmacol
; 465: 116469, 2023 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36918129
3.
Estimated sensitivity profiles of lung cancer specific uncommon BRAF mutants towards experimental and clinically approved kinase inhibitors.
Toxicol Appl Pharmacol
; 453: 116213, 2022 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36049549
4.
Analysis of cellular models of clonal evolution reveals co-evolution of imatinib and HSP90 inhibitor resistances.
Biochem Biophys Res Commun
; 534: 461-467, 2021 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33246559
5.
Emergence of ERBB2 Mutation as a Biomarker and an Actionable Target in Solid Cancers.
Oncologist
; 24(12): e1303-e1314, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31292270
6.
Molecular docking analysis of imine stilbene analogs and evaluation of their anti-aging activity using yeast and mammalian cell models.
J Recept Signal Transduct Res
; 39(1): 55-59, 2019 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31132911
7.
Evolvement of nutraceutical onion plants engineered for resveratrol biosynthetic pathway.
Plant Cell Rep
; 38(9): 1127-1137, 2019 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-31154513
8.
Computational analysis of ABL kinase mutations allows predicting drug sensitivity against selective kinase inhibitors.
Tumour Biol
; 39(5): 1010428317701643, 2017 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-28475010
9.
Synthesis of novel forskolin isoxazole derivatives with potent anti-cancer activity against breast cancer cell lines.
Bioorg Med Chem Lett
; 27(18): 4314-4318, 2017 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28838692
10.
FeCl3 catalysed 7-membered ring formation in a single pot: a new route to indole-fused oxepines/azepines and their cytotoxic activity.
Org Biomol Chem
; 15(20): 4468-4476, 2017 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-28497830
11.
Asymmetric kinase dimer formation is crucial for the activation of oncogenic EGFRvIII but not for ERBB3 phosphorylation.
Cell Commun Signal
; 11: 39, 2013 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-23758840
12.
Metformin exerts antileukemic effects by modulating lactate metabolism and overcomes imatinib resistance in chronic myelogenous leukemia.
FEBS J
; 290(18): 4480-4495, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37171230
13.
AMPK-induced novel phosphorylation of RUNX1 inhibits STAT3 activation and overcome imatinib resistance in chronic myelogenous leukemia (CML) subjects.
Cell Death Discov
; 9(1): 401, 2023 Oct 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37903788
14.
Large-scale pathogenicity prediction analysis of cancer-associated kinase mutations reveals variability in sensitivity and specificity of computational methods.
Cancer Med
; 12(16): 17468-17474, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37409618
15.
Squamous cell carcinoma of the lung: improving the detection and management of immune-related adverse events.
Expert Rev Anticancer Ther
; 22(2): 203-213, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-35034561
16.
Molecular docking analysis reveals differential binding affinities of multiple classes of selective inhibitors towards cancer-associated KRAS mutants.
3 Biotech
; 12(12): 343, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36353445
17.
Synthesis and cytotoxicity of novel 14α-O-(1,4-disubstituted-1,2,3-triazolyl) ester derivatives of andrographolide.
Nat Prod Res
; 35(2): 289-297, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-31219346
18.
Functional analysis of epidermal growth factor receptor (EGFR) mutations and potential implications for EGFR targeted therapy.
Clin Cancer Res
; 15(2): 460-7, 2009 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19147750
19.
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in non-small cell lung cancer harboring uncommon EGFR mutations: Focus on afatinib.
Semin Oncol
; 46(3): 271-283, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31558282
20.
Elucidation of conformational diversity of druggable enzymes and classification of chemical modulators based on inhibitor-bound structures.
J Biomol Struct Dyn
; 37(17): 4563-4568, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30488775