Detalles de la búsqueda
1.
Comparison of biological activities of human antithrombins with high-mannose or complex-type nonfucosylated N-linked oligosaccharides.
Glycobiology
; 26(5): 482-92, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26747427
2.
A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcγRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques.
J Virol
; 86(11): 6189-96, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22457527
3.
KW-2449, a novel multikinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation.
Blood
; 114(8): 1607-17, 2009 Aug 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-19541823
4.
The N-linked oligosaccharide at Fc gamma RIIIa Asn-45: an inhibitory element for high Fc gamma RIIIa binding affinity to IgG glycoforms lacking core fucosylation.
Glycobiology
; 19(2): 126-34, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18952826
5.
Aranorosin and a novel derivative inhibit the anti-apoptotic functions regulated by Bcl-2.
Biochem Biophys Res Commun
; 377(4): 1085-90, 2008 Dec 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-18977202
6.
Conformational significance of EH21A1-A4, phenolic derivatives of geldanamycin, for Hsp90 inhibitory activity.
Bioorg Med Chem Lett
; 18(5): 1588-91, 2008 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18243703
7.
Establishment of a GDP-mannose 4,6-dehydratase (GMD) knockout host cell line: a new strategy for generating completely non-fucosylated recombinant therapeutics.
J Biotechnol
; 130(3): 300-10, 2007 Jun 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-17559959
8.
Correction: Generation and Improvement of Effector Function of a Novel Broadly Reactive and Protective Monoclonal Antibody against Pneumococcal Surface Protein A of Streptococcus pneumoniae.
PLoS One
; 12(2): e0171732, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28166258
9.
Potent Therapeutic Activity Against Peritoneal Dissemination and Malignant Ascites by the Novel Anti-Folate Receptor Alpha Antibody KHK2805.
Transl Oncol
; 10(5): 707-718, 2017 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-28710915
10.
Generation and Improvement of Effector Function of a Novel Broadly Reactive and Protective Monoclonal Antibody against Pneumococcal Surface Protein A of Streptococcus pneumoniae.
PLoS One
; 11(5): e0154616, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27171010
11.
Synthetic inhibitors of proline-rich ligand-mediated protein-protein interaction: potent analogs of UCS15A.
Chem Biol
; 10(5): 443-51, 2003 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-12770826
12.
Discovery and structure-activity relationships of novel piperidine inhibitors of farnesyltransferase.
J Med Chem
; 46(12): 2467-73, 2003 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-12773050
13.
MPC1001 and its analogues: new antitumor agents from the fungus Cladorrhinum species.
Org Lett
; 6(22): 4101-4, 2004 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-15496109
14.
UCS1025A and B, new antitumor antibiotics from the fungus Acremonium species.
Org Lett
; 4(25): 4387-90, 2002 Dec 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-12465894
15.
Evaluation of a fully human monoclonal antibody against multiple influenza A viral strains in mice and a pandemic H1N1 strain in nonhuman primates.
Antiviral Res
; 111: 60-8, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25218949
16.
Treatment response in Kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G.
PLoS One
; 8(12): e81448, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24324693
17.
New molecular and biological mechanism of antitumor activities of KW-2478, a novel nonansamycin heat shock protein 90 inhibitor, in multiple myeloma cells.
Clin Cancer Res
; 16(10): 2792-802, 2010 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20406843
18.
Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types.
Glycobiology
; 17(1): 104-18, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17012310
19.
Design and synthesis of piperidine farnesyltransferase inhibitors with reduced glucuronidation potential.
Bioorg Med Chem
; 15(3): 1363-82, 2007 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17127066
20.
Non-fucosylated therapeutic antibodies: the next generation of therapeutic antibodies.
Cytotechnology
; 55(2-3): 109-14, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19003000