Detalles de la búsqueda
1.
Insulin Signaling Differentially Regulates the Trafficking of Insulin and Amyloid Beta Peptides at the Blood-Brain Barrier.
Mol Pharm
; 21(5): 2176-2186, 2024 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38625027
2.
Amyloid-Beta Peptides 40 and 42 Employ Distinct Molecular Pathways for Cell Entry and Intracellular Transit at the Blood-Brain Barrier Endothelium.
Mol Pharmacol
; 104(5): 203-213, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37541759
3.
Deconvolution of Plasma Pharmacokinetics from Dynamic Heart Imaging Data Obtained by Single Positron Emission Computed Tomography/Computed Tomography Imaging.
J Pharmacol Exp Ther
; 386(1): 102-110, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37221092
4.
Design, Synthesis, and Preliminary Evaluation of [68Ga]Ga-NOTA-Insulin as a PET Probe in an Alzheimer's Disease Mouse Model.
Bioconjug Chem
; 33(5): 892-906, 2022 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-35420782
5.
Distinct Uptake Kinetics of Alzheimer Disease Amyloid-ß 40 and 42 at the Blood-Brain Barrier Endothelium.
J Pharmacol Exp Ther
; 376(3): 482-490, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33303699
6.
Semimechanistic Population Pharmacokinetic Modeling to Investigate Amyloid Beta Trafficking and Accumulation at the BBB Endothelium.
Mol Pharm
; 18(11): 4148-4161, 2021 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34664956
7.
COVID-19 Transmission, Current Treatment, and Future Therapeutic Strategies.
Mol Pharm
; 18(3): 754-771, 2021 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33464914
8.
High-Density Lipoprotein Mimetic Peptide 4F Efficiently Crosses the Blood-Brain Barrier and Modulates Amyloid-ß Distribution between Brain and Plasma.
J Pharmacol Exp Ther
; 375(2): 308-316, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32778535
9.
Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-ß in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice.
Mol Cell Neurosci
; 99: 103390, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31276749
10.
Determination of Rate and Extent of Scopolamine Release from Transderm Scop® Transdermal Drug Delivery Systems in Healthy Human Adults.
AAPS PharmSciTech
; 21(3): 117, 2020 Apr 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-32300962
11.
Apolipoprotein A-I Crosses the Blood-Brain Barrier through Clathrin-Independent and Cholesterol-Mediated Endocytosis.
J Pharmacol Exp Ther
; 369(3): 481-488, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30971477
12.
Cationic carrier peptide enhances cerebrovascular targeting of nanoparticles in Alzheimer's disease brain.
Nanomedicine
; 16: 258-266, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30300748
13.
Design, Development, and Characterization of Imiquimod-Loaded Chitosan Films for Topical Delivery.
AAPS PharmSciTech
; 20(2): 58, 2019 Jan 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30623265
14.
High-density lipoprotein mimetic peptide 4F mitigates amyloid-ß-induced inhibition of apolipoprotein E secretion and lipidation in primary astrocytes and microglia.
J Neurochem
; 147(5): 647-662, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30028014
15.
Sensitive Determination of Fentanyl in Low-Volume Serum Samples by LC-MS/MS.
AAPS PharmSciTech
; 19(7): 2812-2817, 2018 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-30191378
16.
Your brain scan may be a reflection of your genes.
Brain
; 141(9): 2539-2541, 2018 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30169591
17.
Pericyte Control of Gene Expression in the Blood-Brain Barrier Endothelium: Implications for Alzheimer's Disease.
J Alzheimers Dis
; 99(s2): S281-S297, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38393902
18.
Traffic jam at the blood-brain barrier promotes greater accumulation of Alzheimer's disease amyloid-ß proteins in the cerebral vasculature.
Mol Pharm
; 10(5): 1557-65, 2013 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-23249146
19.
Delivery of RNA to the Blood-Brain Barrier Endothelium Using Cationic Bicelles.
Pharmaceutics
; 15(8)2023 Aug 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37631300
20.
Alzheimer's disease amyloid ß-protein mutations and deletions that define neuronal binding/internalization as early stage nonfibrillar/fibrillar aggregates and late stage fibrils.
Biochemistry
; 51(19): 3993-4003, 2012 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22545812