Detalles de la búsqueda
1.
Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin.
Mol Cell
; 70(3): 422-434.e6, 2018 05 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29681499
2.
Analysis of super-enhancer using machine learning and its application to medical biology.
Brief Bioinform
; 24(3)2023 05 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-36960780
3.
Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations.
Mol Cancer
; 23(1): 126, 2024 Jun 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38862995
4.
Application of non-negative matrix factorization in oncology: one approach for establishing precision medicine.
Brief Bioinform
; 23(4)2022 07 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-35788277
5.
Interactions between JARID2 and noncoding RNAs regulate PRC2 recruitment to chromatin.
Mol Cell
; 53(2): 290-300, 2014 Jan 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-24374312
6.
Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome.
Mol Cell
; 53(2): 301-16, 2014 Jan 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-24462204
7.
Nascent RNA interaction keeps PRC2 activity poised and in check.
Genes Dev
; 28(18): 1983-8, 2014 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25170018
8.
Histone methyltransferase SMYD2 selective inhibitor LLY-507 in combination with poly ADP ribose polymerase inhibitor has therapeutic potential against high-grade serous ovarian carcinomas.
Biochem Biophys Res Commun
; 513(2): 340-346, 2019 05 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-30955858
9.
The histone methyltransferase WHSC1 is regulated by EZH2 and is important for ovarian clear cell carcinoma cell proliferation.
BMC Cancer
; 19(1): 455, 2019 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31092221
10.
Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA.
Genes Dev
; 24(23): 2615-20, 2010 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21123648
11.
Advances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance biological interpretability.
Exp Mol Med
; 56(3): 646-655, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38433247
12.
PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway.
Cell Rep
; 42(6): 112519, 2023 06 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37224811
13.
Integrative analysis reveals early epigenetic alterations in high-grade serous ovarian carcinomas.
Exp Mol Med
; 55(10): 2205-2219, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37779141
14.
Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.
Nature
; 444(7121): 953-6, 2006 Dec 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-17128255
15.
The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.
Proc Natl Acad Sci U S A
; 106(3): 755-60, 2009 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-19136632
16.
Automated Endocardial Border Detection and Left Ventricular Functional Assessment in Echocardiography Using Deep Learning.
Biomedicines
; 10(5)2022 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35625819
17.
Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules.
Int J Oncol
; 60(1)2022 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-34913069
18.
The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma.
Commun Biol
; 5(1): 39, 2022 01 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35017636
19.
Medical Professional Enhancement Using Explainable Artificial Intelligence in Fetal Cardiac Ultrasound Screening.
Biomedicines
; 10(3)2022 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-35327353
20.
Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer.
Clin Epigenetics
; 14(1): 147, 2022 11 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36371227